Estenion Tablet 5 mg (Esamlodipine Besilate Hydrate)

Adult dose

This medication should be taken with a sufficient amount of water. For esamlodipine, take 2.5 mg orally once daily, and the dose may be increased up to a maximum of 5 mg per day based on the patient's response. Adjust appropriately according to symptoms.

This medication should not be used in certain patients. For example, it is contraindicated in patients who are allergic to this medication or similar medications, women who are pregnant or breastfeeding, and patients with severe hypotension or cardiac issues. Additionally, caution is needed for patients with severe liver or kidney dysfunction. This medication may cause side effects such as flushing or warmth, fatigue, swelling, headache, dizziness, and indigestion. Rarely, more serious side effects like hypotension, cardiac arrhythmias, skin rash, liver dysfunction, and psychological changes may occur, necessitating immediate consultation with a physician if any abnormal symptoms arise. Abruptly stopping the medication may worsen symptoms, thus the dosage should be gradually reduced according to a doctor's instructions. Patients with heart failure or liver dysfunction should use this medication with extra caution and frequently monitor their blood pressure. It is advisable to take this medication with plenty of water, and caution should be exercised when driving or operating dangerous machinery, as dizziness or drowsiness may occur. There may be interactions when taken with other medications, so it is crucial to consult a physician or pharmacist. Special caution is necessary when taken with grapefruit juice or certain antibiotics and antihypertensive medications. Women who are pregnant or breastfeeding should avoid this medication, and it is recommended for use in children aged 6 years and older only. For elderly patients, the drug concentration may increase, so starting with a low dose and monitoring the condition is advised. Overdose may cause severe hypotension, cardiac issues, and loss of consciousness, requiring immediate emergency care, while gastric lavage or administration of calcium gluconate may be helpful. This medication should be stored out of reach of children, and it is safe not to transfer it into another container.

Serious side effects

Hives, angioedema, severe swelling, severe allergic reactions, itching, angioedema, erythema multiforme, exfoliative dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis, liver abnormalities (jaundice), jaundice, symptoms related to liver dysfunction, paralysis, serious neurological symptoms, thrombocytopenia, leukopenia, difficulty breathing, respiratory distress with cough and fever, severe swelling, urinary anomalies, worsening heart failure

Mild side effects

• Flushing accompanied by warmth
• fatigue
• swelling
• palpitations
• dizziness
• headache
• migraine
• weakness
• abdominal pain
• nausea

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is best to maintain storage temperatures between 1 to 30 degrees Celsius in a cool, dry place.

Appearance

Pale orange heart-shaped tablet with a score line

Package unit

30 tablets/bottle, 300 tablets/bottle