Medication info
Twice Plus Soft Capsule

Twice Plus Soft Capsule

OTC medicationSoft capsule경구
Ingredient · strength
Tocopherol Acetate›500mg / 1 capsuleMagnesium Oxide›250mg / 1 capsuleBenfotiamine›20mg / 1 capsuleThiamine Nitrate›35mg / 1 capsuleSelenium In Dried Yeast›37mg / 1 capsuleGamma-Oryzanol›5mg / 1 capsule
Manufacturer / importer
동방에프티엘(주)
Appearance
Brownish-black oblong soft capsule containing light yellow emulsion
Packaging
60 capsules/box [(10 capsules/PTP*6)], 120 capsules/box [(10 capsules/PTP*12)]
Approval status
Active

MFDS item code 201606414 · Notified 2016.11.01

Summary

Main use
Relief of pain from peripheral circulatory disorders (stiff shoulders, cold extremities) and neuralgia
Who takes it
Adults
Adult dose
For individuals aged 12 years and older, take 1 capsule twice daily.

Ingredients

Manufacturer
동방에프티엘(주)

Efficacy & effects

Relief of pain from peripheral circulatory disorders (stiff shoulders, cold extremities) and neuralgia

  • Physical fatigue
  • decreased physical strength
  • peripheral circulatory disorders
  • menopausal symptoms
  • stiffness in shoulders
  • stiffness in neck
  • numbness in hands and feet
  • cold sensation in hands and feet
  • neuralgia
  • myalgia
  • arthralgia
  • beriberi
View approved original text

This medication contains Vitamin E and Vitamin B1, making it suitable for use during physical fatigue, decrease in physical strength during or after illness, pregnancy and breastfeeding, and old age. It also helps alleviate symptoms of stiffness in the shoulders and neck, numbness and cold sensation in the hands and feet due to peripheral circulatory disorders and menopause. Additionally, it is effective for pain relief such as neuralgia, myalgia, and arthralgia, and improves fatigue in the eyes. This medication is also used for muscle cramps caused by magnesium deficiency. Overall, it is used to alleviate symptoms related to various vitamin deficiencies and replenish physical strength.

How to take

Adult dose

For individuals aged 12 years and older, take 1 capsule twice daily.

Precautions

This medication should not be taken by individuals allergic to certain ingredients, babies under 12 months of age, patients with severe kidney dysfunction, or those allergic to soybean oil, soy, or peanuts. During treatment with this medication, it is advisable not to take medications such as phosphates, calcium salts, oral tetracycline antibiotics, and antacids together. Before taking this medication, individuals with existing diseases, pregnant or breastfeeding women, those with gastrointestinal issues, and those with problems with cardiac or kidney function, hypoalbuminemia, or lipid metabolism disorders must consult their doctor or pharmacist. If unusual symptoms such as gastric discomfort, diarrhea, rash, vomiting, heart rhythm irregularities, dermatitis, hair loss occur during usage, immediate discontinuation and consultation with a healthcare professional is required. Additionally, this medication may alter menstrual cycles or cause increased bleeding, thus women taking oral contraceptives or patients at risk of thrombosis should be cautious as their risk of thrombosis may increase. Overdose may lead to nausea, vomiting, swelling, and cardiac issues, and caution is needed as it may increase serum potassium levels when used with certain diuretics. It is important to follow the prescribed dosage and directions accurately, and it is advisable to avoid teas containing tannins, such as green tea or black tea, before and after administration. Patients with lipid metabolism issues should regularly check their blood lipid levels and adjust the dosage as necessary. Keep this medication out of reach of children, store in a cool and dry place away from direct sunlight, tightly sealed. Also, do not transfer to another container; care should be taken to prevent misuse and to maintain the quality of the medication.

Side effects and when to seek care immediately

Serious side effects

Cardiac arrest (cardiac rhythm arrest), central nervous system function impairment

Mild side effects

Gastric discomfort, diarrhea, constipation, rash, redness, nausea, vomiting, loose stools, red spots, dermatitis, body odor during sweating or breathing, hair loss, impatience, increased menstrual flow or prolonged bleeding, nausea, vomiting, hypernatremia, congestive heart failure, swelling (edema), hyperkalemia

Not everyone experiences these, and they can vary from person to person.

Interactions

Drug interactions

This medication should not be taken with phosphates, calcium salts, oral tetracycline preparations, or antacids. Consult with a doctor or pharmacist if using with oral contraceptives containing estrogen, anti-aldosterone agents, triamterene, and intravenous lipid preparations.

Food interactions

It is advisable not to take this medication together with teas containing tannins, such as green tea and black tea, during and before and after administration.

Storage

This medication can be sensitive to air and moisture, therefore it should be stored in a sealed container. Additionally, it is best stored at room temperature between 1 to 30 degrees Celsius. Proper storage helps maintain the effectiveness and safety of the medication.

Appearance and packaging

Appearance

Brownish-black oblong soft capsule containing light yellow emulsion

Package unit

60 capsules/box [(10 capsules/PTP*6)], 120 capsules/box [(10 capsules/PTP*12)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.