Medication info
Twinfor 40/10 mg

Twinfor 40/10 mg

Prescription medication경구
Ingredient · strength
Telmisartan›40mg / 1 tabletAmlodipine Besylate›13.87mg / 1 tablet
Manufacturer / importer
환인제약(주)
Appearance
White to light yellow and light blue, double convex oval-shaped film-coated tablet
Packaging
30 tablets (10 tablets/PTP × 3), 30 tablets/bottle
Approval status
Active

MFDS item code 201606341 · Approved 2016.10.28 · Insurance code 657202940

Summary

Main use
Improvement in blood pressure control with the combination of Amlodipine or Telmisartan for essential hypertension
Who takes it
Adults · Children
Adult dose
The recommended dose of this medication is 1 tablet once daily, to be taken with water regardless of meals. It is recommended to take it at the same time each day (e.g., in the morning). In patients with renal impairment: For mild to moderate renal impairment, dose adjustment is not necessary, but for severe renal impairment, treatment should start at a lower dose with gradual titration. In patients with hepatic impairment: The daily dose of Telmisartan for patients with mild or moderate hepatic impairment should not exceed 40 mg.
Child dose
The safety and efficacy of this medication have not been established in pediatric patients under the age of 18, and its administration is not recommended.

Ingredients

Manufacturer
환인제약(주)

Efficacy & effects

Improvement in blood pressure control with the combination of Amlodipine or Telmisartan for essential hypertension

  • Essential hypertension
View approved original text

This medication is used for patients with essential hypertension who do not achieve adequate blood pressure control with monotherapy of Amlodipine or Telmisartan. It effectively controls blood pressure, reduces the strain on the heart and blood vessels, and helps prevent complications. Therefore, it plays an important role in blood pressure management and is beneficial in the treatment of hypertension.

How to take

Adult dose

The recommended dose of this medication is 1 tablet once daily, to be taken with water regardless of meals. It is recommended to take it at the same time each day (e.g., in the morning). In patients with renal impairment: For mild to moderate renal impairment, dose adjustment is not necessary, but for severe renal impairment, treatment should start at a lower dose with gradual titration. In patients with hepatic impairment: The daily dose of Telmisartan for patients with mild or moderate hepatic impairment should not exceed 40 mg.

Child dose

The safety and efficacy of this medication have not been established in pediatric patients under the age of 18, and its administration is not recommended.

Precautions

This medication can cause serious harm to the fetus, especially in the second and third trimesters, so women who are pregnant should not take it. If pregnancy is confirmed, this medication should be discontinued as soon as possible. This medication should not be administered to individuals with hypersensitivity to certain components, pregnant women, women who may become pregnant, nursing mothers, or patients with severe liver or heart conditions. Additionally, patients with severe hypotension or in shock, as well as patients with unstable heart failure after acute myocardial infarction, should not use this medication. Caution should be exercised when using this medication in patients with impaired liver function or obstructive biliary disease, and dosage adjustment may be necessary in cases of decreased liver function. Patients with gastrointestinal disease should be cautious due to the risk of gastrointestinal bleeding. Patients with impaired kidney function or renal artery hypertension should also be carefully administered this medication due to the risk of further kidney function deterioration. This medication should be used with caution in the elderly, and slow dosage adjustments are recommended. While taking this medication, side effects such as dizziness or drowsiness may occur, so caution is needed when driving or operating dangerous machinery. Additionally, because this medication has a strong effect on lowering blood pressure, hypotension may occur, and in such cases, the patient should be laid down and intravenous therapy may be necessary. Hyperkalemia may occur, so potassium levels in the blood should be regularly monitored, especially when used in conjunction with potassium supplements or potassium-containing medications. The risk of deteriorating kidney function, hypotension, and hyperkalemia may increase when this medication is combined with other antihypertensive agents, so it should be done under a doctor's guidance. In case of overdose, serious hypotension or heart problems may occur, so immediate contact with a healthcare facility is necessary for appropriate treatment. This medication is not recommended for children as its safety and efficacy have not been adequately established.

Side effects and when to seek care immediately

Serious side effects

  • Urticaria
  • severe swelling (edema)
  • difficulty breathing
  • liver anomalies (jaundice)
  • severe allergic reactions
  • severe skin reaction
  • serious neurological symptoms
  • severe edema or urinary abnormalities
  • fainting
  • septicemia
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  • angioedema
  • toxic skin rash
  • angioedema
  • erythema multiforme
  • urticaria
  • exfoliative dermatitis
  • Steven-Johnson syndrome
  • angioedema
  • hepatitis
  • jaundice
  • myocardial infarction
  • ventricular tachycardia
  • arrhythmia
  • atrial fibrillation
  • vasculitis
  • difficulty breathing
  • interstitial pneumonia

Mild side effects

  • Dizziness
  • peripheral edema
  • upper respiratory tract infection
  • urinary tract infection
  • anemia
  • hyperkalemia
  • hypoglycemia
  • depression
  • insomnia
  • visual impairment
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  • palpitations
  • flush
  • cough
  • changes in bowel habits
  • abdominal pain
  • indigestion
  • nausea
  • vomiting
  • itching
  • rash
  • hair loss
  • joint swelling
  • muscle cramps
  • back pain
  • erectile dysfunction
  • weakness
  • fatigue
  • increased liver enzymes
  • elevated blood creatinine
  • weight gain
  • weight loss
  • increased blood uric acid
  • decreased platelet count
  • decreased platelet count
  • blood

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light, so it should be stored in a light-resistant container. Additionally, to store the medication safely, it is important to keep it at room temperature, between 1 degree and 30 degrees Celsius.

Appearance and packaging

Appearance

White to light yellow and light blue, double convex oval-shaped film-coated tablet

Package unit

30 tablets (10 tablets/PTP × 3), 30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.