Twincombi Tablets 40/5mg

Adult dose

The recommended dosage for adults is one tablet once daily, to be taken with water without regard to meals. It is advisable to take it at the same time each day (e.g., in the morning). If blood pressure is not adequately controlled, the dosage can be adjusted to 40/5mg, 80/5mg, or 40/10mg based on the individual active ingredient's dosage. In patients with renal impairment, treatment should begin with a low dose in severe cases, gradually increasing the dosage, and patients should be monitored regularly for serum potassium and creatinine levels. Telmisartan is not removed by dialysis.

Child dose

Safety and efficacy for patients under 18 years of age have not been established, hence the use of this medication is not recommended in children.

This medication can cause serious harm to the fetus if taken during pregnancy, particularly in the second and third trimesters; therefore, it should not be taken by pregnant women or those who may become pregnant. Furthermore, it should not be used by individuals with known allergies to the active ingredients, severe liver or heart problems, hypotension, or certain kidney diseases. Caution is required when administering this medication to patients with impaired liver function or gastrointestinal diseases, and patients with decreased kidney function should be regularly monitored for kidney function. Special caution is necessary when administering to the elderly or patients with heart failure, and additional testing may be needed for diabetic patients as they are at increased risk for cardiovascular disease. This medication can cause drowsiness or dizziness; therefore, caution is advised when driving or operating machinery. Additionally, this medication can interact with other drugs, so patients taking other medications must inform their healthcare provider. In case of overdose, symptoms such as hypotension and cardiac issues may arise, necessitating immediate medical attention. This medication is not recommended for children, and it is also advisable that breastfeeding women avoid using it. When storing, keep it out of reach of children and open the packaging just before use to ensure product quality.

Serious side effects

Hives, severe swelling (edema), cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, difficulty breathing or shortness of breath, asthma attacks, breathing abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, significantly reduced urine output,

Mild side effects

Dizziness, peripheral edema, syncope, drowsiness, headache, sensory abnormalities, taste disturbances, tremor, visual disturbances (including diplopia), vertigo, tinnitus, palpitations, bradycardia, tachycardia, flushing, hypotension, orthostatic hypotension, cough, difficulty breathing, rhinitis, changes in bowel habits (including diarrhea and constipation), abdominal pain, dyspepsia, nausea, vomiting, dry mouth, itching, sweating, rash, hair loss, purpura, skin discoloration, eczema, erythema, joint swelling, muscle cramping,

This medication is sensitive to light and should be stored in a special container that protects it from light. Additionally, it should be kept at room temperature between 1 degree Celsius and 30 degrees Celsius. Proper storage will maintain the drug's effectiveness and ensure safe use.

Appearance

Biconvex oval-shaped double tablet, white to light yellow and light blue

Package unit

30 tablets (10 tablets/PTP x 3), 30 tablets/bottle