Medication info
Twincombi Tablets 40/10mg

Twincombi Tablets 40/10mg

Prescription medication경구
Ingredient · strength
Telmisartan›40mg / 1 tabletAmlodipine Besylate›13.87mg / 1 tablet
Manufacturer / importer
대원제약(주)
Appearance
White to slightly yellow and light blue, double convex oval tablets.
Packaging
30 tablets (10 tablets/PTP x 3), 30 tablets/bottle
Approval status
Active

MFDS item code 201606306 · Approved 2016.10.27 · Insurance code 671806380

Summary

Main use
Improvement in blood pressure control for essential hypertension.
Who takes it
Adults · Children
Adult dose
The recommended dose of this medication is one tablet once daily, to be taken with water, regardless of meals. It is recommended to take it at the same time every day (e.g., in the morning). In patients with severe renal impairment, treatment should be initiated at a lower dosage with gradual titration. In patients with liver impairment, the daily dose of telmisartan should not exceed 40 milligrams. Elderly patients (over 75 years) require careful dosage adjustments.
Child dose
The safety and efficacy of this medication in pediatric patients below the age of 18 have not been established, and its use is not recommended.

Ingredients

Manufacturer
대원제약(주)

Efficacy & effects

Improvement in blood pressure control for essential hypertension.

  • Essential hypertension
View approved original text

This medication is used for patients with essential hypertension who do not have sufficient blood pressure control with monotherapy of amlodipine or telmisartan. It helps to manage blood pressure more effectively by combining both medications. This contributes to stabilizing blood pressure and reducing the risk of cardiovascular complications. It is used to improve the patient's blood pressure control status.

How to take

Adult dose

The recommended dose of this medication is one tablet once daily, to be taken with water, regardless of meals. It is recommended to take it at the same time every day (e.g., in the morning). In patients with severe renal impairment, treatment should be initiated at a lower dosage with gradual titration. In patients with liver impairment, the daily dose of telmisartan should not exceed 40 milligrams. Elderly patients (over 75 years) require careful dosage adjustments.

Child dose

The safety and efficacy of this medication in pediatric patients below the age of 18 have not been established, and its use is not recommended.

Precautions

This medication can cause serious harm to the fetus when taken during pregnancy, especially in the second and third trimesters, so it should not be taken by pregnant women or women who may become pregnant. This medication should not be administered to patients with certain diseases or drug allergies, severe liver impairment or cardiac issues, and certain kidney diseases. Patients with impaired liver function, gastrointestinal diseases, renal artery hypertension, elderly patients, and others should use this medication with special caution. Taking this medication may commonly result in side effects such as dizziness or swelling, and serious side effects may rarely occur. Patients should consult medical professionals immediately if any abnormal symptoms appear. During treatment, there is a risk of hypotension, hyperkalemia, and changes in kidney function, hence regular monitoring of blood pressure and blood tests is necessary. This medication can interact with other drugs, so if you are taking any other medications, be sure to inform your doctor or pharmacist. Use of this medication should be avoided during pregnancy or breastfeeding, and it should be discontinued immediately if pregnancy is confirmed. The safety and efficacy of this medication in children or adolescents under the age of 18 have not been sufficiently established, and it is not recommended. In elderly patients, doses should be adjusted and used with caution, and overdose may result in severe hypotension or cardiac function deterioration requiring immediate emergency treatment. Keep this medication out of the reach of children and store it in its original packaging to maintain safety.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, severe skin reactions, shortness of breath, liver dysfunction, liver damage, yellowing of the skin or eyes (jaundice), extreme fatigue, jaundice, sudden and severe headaches, thunderclap headaches, seizures, altered consciousness, vision abnormalities, paralysis, severe.

Mild side effects

  • Dizziness
  • peripheral edema
  • upper respiratory tract infections
  • urinary tract infections
  • anemia
  • hyperkalemia
  • hypoglycemia
  • hyponatremia
  • hyperglycemia
  • depression
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  • insomnia
  • mood changes
  • anxiety
  • confusion
  • drowsiness
  • migraine
  • headache
  • sensory disturbance
  • peripheral neuropathy
  • visual impairment
  • vertigo
  • tinnitus
  • palpitations
  • bradycardia
  • tachycardia
  • flushing
  • hypotension
  • orthostatic hypotension
  • cough
  • abdominal pain
  • dyspepsia
  • nausea
  • vomiting
  • dry mouth
  • pruritus
  • sweating
  • rash
  • hair loss.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a special container to protect it from light and air. Additionally, it is important to maintain a cool room temperature, between 1 degree and 30 degrees Celsius, when storing the medication. This will help to preserve the effectiveness of the medication for a longer period.

Appearance and packaging

Appearance

White to slightly yellow and light blue, double convex oval tablets.

Package unit

30 tablets (10 tablets/PTP x 3), 30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

No questions yet.

For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.