Hyaluna Injection (Pre-filled) (Sodium Hyaluronate)

Adult administration

Usually administered 1 vial once a week for 3 consecutive weeks into the knee joint or shoulder joint (shoulder joint cavity, subacromial bursa, or biceps tendon sheath) but may adjust the frequency according to symptoms.

This medication should not be used by individuals who have previously experienced allergic reactions to any component of this medication. Special caution should be exercised for individuals who have had allergic reactions to other medications or who have liver function problems or have experienced liver disease in the past. Additionally, if there is a skin condition or infection at the injection site, care should be taken during intra-articular injection. Serious side effects such as shock symptoms may occur while using this drug; thus, treatment should be stopped immediately and appropriate treatment should be sought if any abnormal symptoms appear. Allergic reactions may manifest as swelling of the face or eyelids, rashes, hives, or itching. If these symptoms occur, administration should be halted, and treatment should be provided. Temporary pain, swelling, redness, warmth, or severe pressure may occur at the injected joint site; such symptoms should be reported. Occasionally, symptoms such as nausea, vomiting, and fever may appear. In cases of severe arthritis, it is advisable to use this medication after inflammation has subsided and stabilization of the injection site after administration can be beneficial. If the injectable solution leaks out of the joint, pain may occur; therefore, it should be accurately injected within the joint. Sterile conditions should be maintained during the injection, and administration should be limited to 3 times if symptoms do not improve. If there is excess joint fluid, the fluid may be aspirated as needed before administration. This drug is not used for intravenous administration or ophthalmic use, and it is advisable to use a needle gauge of approximately 22-23. Additionally, care should be taken as it may react with certain disinfectants to produce precipitates. During pregnancy or when there is a possibility of pregnancy, this medication should be used cautiously only when the benefits outweigh the risks. As this medication may be passed through breast milk, breastfeeding should be avoided during administration. Safety has not been established for children, hence it should be used cautiously only if necessary. Elderly patients may have impaired physical function, thus careful use is required.

Serious side effects

• Hives
• swelling (face, eyelids, etc.)
• symptoms of shock.

Mild side effects

• Facial rash
• itching
• pain
• swelling
• redness
• warmth
• severe local pressure
• nausea
• vomiting
• fever.

This medication should be stored in a tightly sealed container to prevent air or moisture from entering. It is recommended to maintain a storage temperature between 1 and 30 degrees Celsius. Storing it this way will help preserve the medication's efficacy for a longer period.

Appearance

A colorless, transparent, and viscous liquid contained in a glass or plastic vial (pre-filled syringe) sealed with rubber stoppers at both ends.

Package unit

3 vials (2.0 mL/1 vial X 3)