Crocsen Soft Capsule (Clonixin Lysinate)

Adult dose

Adults: Administer 125∼250 mg per dose orally 3 times daily as clonixin lysinate.

This medication should be consulted with a doctor or pharmacist before use for individuals who regularly consume more than three drinks a day. Consuming this medication while frequently drinking alcohol increases the risk of gastrointestinal bleeding. This medication may pose risks to the cardiovascular system and could trigger serious thrombotic reactions such as myocardial infarction or stroke. Individuals with cardiovascular disease or risk factors should take extra care and closely monitor cardiovascular symptoms during use. This medication may cause severe adverse reactions, including gastrointestinal bleeding, ulcers, and perforations, thus gastrointestinal symptoms should be monitored closely while taking it. Elderly patients should be especially cautious as they are at higher risk for gastrointestinal adverse reactions. Patients with peptic ulcers or allergies to any component of this medication should not take it, and those with a history of asthma or allergic reactions should also avoid its use. Pregnant women or those who may become pregnant, patients with severe liver impairment, kidney impairment, or heart failure should not take this medication. The risk of side effects can increase when this medication is taken alongside other nonsteroidal anti-inflammatory drugs (NSAIDs), and co-administration should be avoided. Additionally, there may be interactions with ACE inhibitors, aspirin, diuretics, lithium, methotrexate, anticoagulants, etc., so caution is needed. It is advisable to avoid breastfeeding while taking this medication, and consult a physician if breastfeeding. If symptoms such as nausea, vomiting, abdominal pain, skin rash, blood abnormalities, liver dysfunction, or drowsiness occur during use, discontinue use immediately and consult a doctor. This medication should be used for the shortest period and at the lowest effective dose, while long-term use necessitates regular blood tests and liver/kidney function tests. Patients with hypertension or heart failure should monitor blood pressure and fluid status closely during treatment. This medication serves as a symptomatic treatment to alleviate inflammatory symptoms but does not treat the underlying cause. If severe skin rashes or itching occur, discontinue use immediately. Before and during the use of this medication, consult thoroughly with a doctor or pharmacist, and seek professional help if any unusual symptoms arise. Store in a safe place out of reach of children and avoid transferring to other containers.

Gastrointestinal bleeding, severe cardiovascular thrombotic response, myocardial infarction, stroke, bleeding from the stomach or intestines, ulcer, perforation, nausea, vomiting, diarrhea, constipation, abdominal pain, peptic ulcer, shock, rash, itching, anemia, increased AST, increased ALT, drowsiness, headache, dizziness, cold sweat, chill, abnormal euphoria, jaundice, fulminant hepatitis, liver necrosis, liver failure, anemia, exfoliative dermatitis, mucocutaneous syndrome, toxic epidermal necrolysis, severe bronchospasm

Drug interactions

Do not take this medication with nonsteroidal anti-inflammatory drugs (NSAIDs), ACE inhibitors or angiotensin II receptor antagonists, aspirin, diuretics, lithium, methotrexate, coumarin anticoagulants (such as warfarin), cyclosporine and tacrolimus, antiplatelet agents, selective serotonin reuptake inhibitors (SSRIs), corticosteroids. Patients taking misoprostol should consult a doctor before use.

Store this medication in a tightly closed container to protect it from air or moisture. It is recommended to maintain a storage temperature between 1°C and 30°C.

Appearance

A transparent blue oval soft capsule containing a yellowish transparent liquid.

Package unit

10 capsules (10 capsules/PTP X 1)