Medication info
Oparon Tablet (Limaprost Aldex)

Oparon Tablet (Limaprost Aldex)

Prescription medicationTablet
Ingredient · strength
Limaprost Alfadex›166.67μg / 1 tablet
Manufacturer / importer
Kyungbo Pharmaceutical Co., Ltd.
Appearance
White round tablet
Packaging
84 tablets (21 tablets/Alu-AluX4)
Approval status
Active

MFDS item code 201606187 · Approved 2016.10.19 · Insurance code 665002170

Summary

Main use
Relief of ischemic symptoms of Buerger's disease; improvement of lower-limb symptoms and walking ability in acquired lumbar spinal stenosis
Who uses it
Adults
Adult dosage
For improvement of ischemic symptoms such as ulcers, pain, and coldness caused by thromboangiitis obliterans (Buerger's disease), the usual adult dose is 2 tablets orally 3 times daily. For improvement of subjective symptoms (lower limb pain and numbness) and walking ability in patients with acquired lumbar spinal canal stenosis (normal SLR test and bilateral intermittent claudication), the usual adult dose is 1 tablet orally 3 times daily. Adjust the dose appropriately according to age and symptoms.

Ingredients

Manufacturer
Kyungbo Pharmaceutical Co., Ltd.

Efficacy & effects

Relief of ischemic symptoms of Buerger's disease; improvement of lower-limb symptoms and walking ability in acquired lumbar spinal stenosis

  • Ulcers
  • pain
  • cold sensation
  • lower limb pain
  • lower limb numbness
View approved original text

This medication helps improve ischemic symptoms such as ulcers, pain, and cold sensations caused by obstructive thromboangiitis, commonly known as Buerger's disease. It also alleviates subjective symptoms like lower limb pain and numbness in patients with acquired lumbar spinal stenosis and enhances walking ability. Therefore, this drug is effective in improving vascular and nerve-related symptoms.

Dosage and Administration

Adult dosage

For improvement of ischemic symptoms such as ulcers, pain, and coldness caused by thromboangiitis obliterans (Buerger's disease), the usual adult dose is 2 tablets orally 3 times daily. For improvement of subjective symptoms (lower limb pain and numbness) and walking ability in patients with acquired lumbar spinal canal stenosis (normal SLR test and bilateral intermittent claudication), the usual adult dose is 1 tablet orally 3 times daily. Adjust the dose appropriately according to age and symptoms.

Precautions

This medication should absolutely not be used by women who are pregnant or may become pregnant. This drug contains lactose, so individuals with genetic conditions like galactose intolerance, lactase deficiency, and glucose-galactose malabsorption should not take it. Use this drug carefully in patients with bleeding tendencies or those taking antiplatelet drugs, thrombolytics, or anticoagulants. While taking this medication, hypersensitivity symptoms such as skin rash or itching may occur; if such symptoms arise, stop taking the drug immediately. Bleeding may occur rarely; if bleeding symptoms appear, stop taking the medication immediately and consult a physician. Gastrointestinal symptoms such as diarrhea, nausea, abdominal pain, loss of appetite, and heartburn may occur, so caution is needed. Liver function abnormalities may occur, so liver enzyme levels should be monitored. Symptoms such as palpitations, hypotension, and cyanosis of the hands and feet may occur rarely, so caution is needed. Various side effects like headache, facial flushing, dizziness, feverish sensation, body tremors, swelling, and anemia may occur. Patients with lumbar spinal stenosis should observe symptom changes and decide whether to continue medication; the efficacy of this drug may not be certain in severe patients requiring surgery. Safety during pregnancy has not been confirmed, and uterine contractions have been reported in animal studies, so it should not be taken during pregnancy. Safety for children has not been confirmed, and there is no experience in use. Elderly individuals may have decreased physical function, so dosage adjustments and caution are necessary. High-dose administration in healthy adults may temporarily lower blood pressure, so caution should be exercised.

Side effects

  • Rash
  • pruritus
  • bleeding
  • diarrhea
  • nausea
  • abdominal discomfort
  • abdominal pain
  • loss of appetite
  • heartburn
  • vomiting
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  • abdominal bloating
  • elevated AST (GOT)
  • elevated ALT (GPT)
  • palpitations
  • peripheral cyanosis
  • hypotension
  • headache
  • facial flushing
  • dizziness
  • fever
  • generalized weakness
  • edema
  • mastitis
  • tremors
  • hirsutism
  • anemia

Not everyone experiences these, and they can vary from person to person.

Storage

This drug should be stored in a tightly closed container to protect it from air and moisture. Additionally, it is best stored at room temperature between 1 to 30 degrees Celsius.

Appearance and packaging

Appearance

White round tablet

Package unit

84 tablets (21 tablets/Alu-AluX4)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.