Pinesack Soft Capsule (Clonixin Lysinate)

Adult dose

Adults: Administer 125∼250 mg per dose orally 3 times daily as clonixin lysinate.

This medication can cause serious side effects such as gastrointestinal bleeding if taken by individuals who regularly consume more than three alcoholic drinks per day; therefore, consultation with a physician or pharmacist is essential. Additionally, this medication may increase the risk of cardiovascular disease, so those with a history of heart disease or stroke or risk factors should be particularly cautious. Gastrointestinal adverse reactions such as bleeding, ulcers, and perforations may also occur; hence, elderly patients or those with a history of gastrointestinal disorders must consult a healthcare professional before use. Patients with peptic ulcers, known allergies to this medication or its components, or past allergic reactions to aspirin or asthma should avoid taking it. Pregnant women or those who may become pregnant, patients with severe liver impairment, kidney disorders, heart failure, or inflammatory bowel disease should also refrain from taking this medication. Concurrent use with other non-steroidal anti-inflammatory drugs (NSAIDs), ACE inhibitors, aspirin, diuretics, lithium, methotrexate, anticoagulants, and others may increase the risk of side effects due to interactions, so they should not be used together. While taking this medication, if symptoms such as gastrointestinal bleeding, gastrointestinal symptoms, skin rashes, respiratory difficulties, anemia, liver function abnormalities, or neurological symptoms occur, the use should be discontinued immediately and a physician consulted. Regular blood tests and liver and kidney function tests are necessary for long-term use, and administration should be halted at any sign of abnormal symptoms. It is recommended that breastfeeding women either avoid this medication or discontinue breastfeeding during treatment. When using this medication, it is best to use the lowest possible dose for the shortest duration and to consider combining it with other treatments.

Gastrointestinal bleeding, severe cardiovascular thrombotic reactions, myocardial infarction, stroke, bleeding from the stomach or intestines, ulcers, perforation, nausea, vomiting, diarrhea, constipation, abdominal pain, peptic ulcers, perforation, shock, rash, itching, anemia, elevated AST, elevated ALT, drowsiness, headache, dizziness, cold sweat, chills, abnormal euphoria, jaundice, fulminant hepatitis, liver necrosis, liver failure, anemia, skin rash, exfoliative dermatitis, mucocutaneous syndrome, toxic epidermal necrolysis, severe bronchospasm

Drug interactions

Do not take this medication together with other non-steroidal anti-inflammatory drugs (NSAIDs), ACE inhibitors or angiotensin II receptor antagonists, aspirin, diuretics, lithium, methotrexate, coumarin-based anticoagulants (such as warfarin), cyclosporine and tacrolimus, antiplatelet agents, and selective serotonin reuptake inhibitors (SSRIs), corticosteroids. Patients taking Misoprostol should consult before taking.

Store this medication in a tightly sealed container to protect it from air and moisture. It is advisable to maintain room temperature between 1°C and 30°C. This will help preserve the medication’s effectiveness for a longer period.

Appearance

A blue transparent oval soft capsule containing a slightly yellow transparent liquid

Package unit

10 capsules/PTP