Doublezyme Tablet

Adult dose

Adults: 2 tablets per dose, 3 times daily after meals

This medication should not be used by patients undergoing dialysis treatment. This medication contains lactose, so it should not be administered to patients with genetic issues such as lactose intolerance, lactase deficiency, or glucose-galactose malabsorption syndrome. Patients with allergies or hypersensitivity to soybean oil, soybeans, or peanuts should not take this medication. Patients who have previously experienced allergic reactions from this medication or are taking other drugs should use it cautiously. Patients with kidney or liver function issues should also use it with caution, and patients receiving treatment should consult a doctor before taking it. Patients with low phosphate levels or metabolic abnormalities involving fats, hyperlipidemia, diabetic dyslipidemia, or pancreatitis should also use it carefully. If symptoms of allergy such as rash or itching occur while taking this medication, use should be stopped immediately and a specialist should be consulted. Rarely, symptoms such as drowsiness, dizziness, headache, or fatigue may occur; if these symptoms appear, discontinue use and consult a physician. Constipation or dry mouth may also occur rarely, so caution is needed. Rapid heart rate may occur rarely, and liver function test values may rise. Patients with high blood pressure, elderly patients, or those with heart or kidney issues, or edema, must consult a doctor or pharmacist before taking this medication. During treatment, if symptoms such as decreased urine output, swelling of the face or limbs, heaviness of eyelids, stiffness of hands, raised blood pressure, or headache occur, discontinue use immediately and consult a specialist. Long-term use may lead to side effects such as hypokalemia, increased blood pressure, fluid retention, edema, and weight gain, so blood potassium levels should be monitored regularly. Hypokalemia may lead to muscular weakness, limb cramps, or paralysis, so if such symptoms arise, use should be discontinued. Combining with potassium-containing drugs or medications containing licorice, as well as loop and thiazide diuretics, increases the risk of side effects, so caution is required. It is essential to follow the prescribed dosage and administration; if symptoms do not improve after taking for more than two weeks, consult a specialist. Avoid long-term use, and patients with a history of kidney disease must consult before use. Patients at risk of fat overload should check their blood lipid levels and adjust dosage as necessary. Do not take this medication in combination with gastrointestinal analgesics or antispasmodics. This medication should not be administered to children under the age of 15, nor to pregnant or breastfeeding women. When storing, keep it out of reach of children in a cool, dry place away from direct sunlight, and it is advisable not to transfer it to another container to maintain quality.

Serious side effects

Decreased urine output, swelling of the face or limbs, elevated blood pressure, headache (possible severe neurological symptoms), weakness, limb cramps, paralysis (symptoms of myopathy)

Mild side effects

• Rash
• itching
• drowsiness
• dizziness
• fatigue
• headache
• constipation
• dry mouth
• palpitations
• elevated GOT

Drug interactions

This medication should not be taken with gastrointestinal analgesics or antispasmodics. If taken with potassium-containing preparations, licorice-containing preparations, or preparations containing glycyrrhizin or its salts, consult a physician or pharmacist. Additionally, consultation is required when taken with loop diuretics (furosemide, ethacrynic acid) and thiazide diuretics (trichlormethiazide).

This medication is sensitive to light, so it should be stored in a container that does not allow light in. Moreover, it is advisable to store the medication at room temperature, ideally between 1 and 30 degrees Celsius, to maintain its effectiveness.

Appearance

Green round film-coated tablet

Package unit

10 tablets (10 tablets/PTP packaging X 1)