Syubat Tablet 10/10 mg (Ezetimibe, Rosuvastatin)

Adult dose

This medication should be taken once daily, regardless of meals. The initial recommended dose is 10/5 mg once daily. For patients requiring more substantial LDL cholesterol reduction, the dosage can be adjusted. After dosage adjustment, the lipid levels should be checked at intervals of more than four weeks, and it can be increased up to a maximum daily dose of 10/20 mg.

This medication can affect muscles and, rarely, cause rhabdomyolysis, leading to acute renal failure. Therefore, if symptoms of severe muscle pain or myopathy occur, treatment should be stopped immediately, and medical consultation is required. This medication may be contraindicated or require caution for patients with specific diseases or taking certain medications. In particular, patients with liver disease, renal impairment, muscle disease, pregnant or nursing women should not take this medication. Additionally, this medication contains lactose, so patients with lactose intolerance should not take it. Regular liver function and muscle-related tests should be performed during treatment, and any unusual symptoms should be reported to medical staff promptly. Care must be taken when consuming alcohol excessively or if there is a problem with liver function. This medication may interact with other drugs, so if other medications are being taken, it is essential to inform the healthcare provider. Women who are pregnant or potentially pregnant should use appropriate contraception while taking this medication, and if pregnancy is confirmed, they should stop taking it immediately. Special care is needed when administering this medication to children or the elderly, particularly those over 65, as they may have a higher risk of myopathy. This medication may cause dizziness as a side effect when driving or operating machinery, so caution is needed. In case of overdose, there is no specific antidote, so treatment should be symptomatic, and monitoring of liver function and muscle enzyme levels is necessary. Keep out of reach of children, and do not transfer to other containers.

Serious side effects

Hypersensitivity reactions including urticaria and angioedema, edema, facial swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blistering, skin shedding, oral/ocular mucosal pain, severe skin adverse reactions, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), jaundice, hepatitis, toxic hepatitis, liver abnormalities, acute hepatitis, acute renal failure, oliguria,

Mild side effects

• Headache
• arthralgia
• myalgia
• dizziness
• nasopharyngitis
• fatigue
• itching
• rash
• pruritus
• constipation

This medication should be stored in a tightly closed container to prevent air or moisture from entering. It is best to maintain the storage temperature between 1°C and 30°C.

Appearance

Light pink oval film-coated tablet

Package unit

30 tablets/box [10 tablets/PTP X 3]