Ezrovastatin Tablet 10/5 mg

Adult dose

This medication is administered once daily without regard to meals. For primary hypercholesterolemia, an initial dose of 10/5 mg once daily is recommended. For patients requiring greater reduction of LDL-cholesterol, the dose can be adjusted to range between 10/5 mg and 10/20 mg per day. After starting treatment or adjusting the dose, check serum lipid levels at intervals of at least 4 weeks; the maximum dose is 10.

This medication may cause rare side effects that can affect the muscles, so if severe muscle pain or weakness occurs, notify a doctor immediately. This medication may affect liver function; therefore, patients with liver issues or abnormally high liver enzyme levels should not use it and should have regular liver function tests during treatment. Do not use this medication in patients with severe kidney impairment, and those with kidney problems should use it cautiously under medical supervision. Women who are pregnant or may become pregnant, as well as breastfeeding women, should not take this medication, and women of childbearing age should use appropriate contraception. This medication should not be administered to patients with certain genetic lactose intolerance and should also not be used in patients with allergic reactions or muscle disease. Special caution is required for elderly patients or those with liver disease or alcohol addiction when administering this medication; interactions with other drugs may increase the risk of side effects, so consult a doctor. While taking this medication, if symptoms such as muscle pain, fatigue, or fever occur, consult a doctor immediately. Serious skin reactions or muscle weakness may occur, so careful monitoring is necessary. Dizziness may occur when driving or operating machinery, so caution is required. This medication may interact with other drugs, so inform healthcare providers about all medications being taken, especially anticoagulants, fibrates, and certain antibiotics, due to precautions needed during combination therapy. In case of overdose, there is no specific antidote; therefore, seek hospital treatment immediately for symptomatic management along with liver function and blood tests. Keep out of the reach of children and do not transfer to another container for safety.

Serious side effects

Hives, swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blistering, skin peeling, pain of oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, breathing abnormalities associated with cough and fever, yellowing of the skin or eyes (jaundice), extreme fatigue, sudden and severe headache, lightning-type headache, seizures, confusion of consciousness, visual disturbances, paralysis, significantly reduced urine output

Mild side effects

• Nasopharyngitis
• joint pain
• headache
• increased ALT
• increased AST
• muscle pain
• edema
• elevated blood bilirubin
• acneiform dermatitis
• pruritus

This medication may be sensitive to air and moisture, so it should be stored in a tightly closed container. It is important to maintain a storage temperature between 1 to 30 degrees Celsius to keep the medication effective longer.

Appearance

White to almost white round film-coated tablet

Package unit

30 tablets (15 tablets/PTP × 2)