Medication info

Jeil Fatless Injection (L-Carnitine)

Prescription medicationInjectionsIntravenous injection
Ingredient · strength
L-Carnitine›0.2g / 1mL
Manufacturer / importer
Jeil Pharmaceutical Co., Ltd.
Appearance
A clear colorless to pale yellow liquid contained in a brown transparent glass ampoule.
Packaging
5 mL/ampoule X 25 ampoules
Approval status
Active

MFDS item code 201606030 · Notified 2016.10.12

Summary

Main use
Treatment of carnitine deficiency, ischemic myocardial metabolic disorders, and carnitine deficiency in patients undergoing hemodialysis
Who receives it
Adults
Adult administration
1. Primary and secondary carnitine deficiency Myocardial metabolic disorder due to ischemic heart disease: angina pectoris, acute myocardial infarction Adults: Administer 2~3 g of L-carnitine daily in 2~3 divided doses by intramuscular or intravenous injection. Adjust the dose as appropriate according to age and symptoms. 2. Treatment of carnitine deficiency in patients with end-stage renal disease undergoing hemodialysis Initially, administer 10~20 mg/kg intravenously over 2~3 minutes at the end of each hemodialysis session. However, the dose may be adjusted according to the plasma L-carnitine level before hemodialysis.

Ingredients

Manufacturer
Jeil Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of carnitine deficiency, ischemic myocardial metabolic disorders, and carnitine deficiency in patients undergoing hemodialysis

  • Primary carnitine deficiency
  • secondary carnitine deficiency
  • angina
  • acute myocardial infarction
  • carnitine deficiency in patients with end-stage kidney disease.
View approved original text

This medication is used to treat primary and secondary carnitine deficiency. It is also effective for myocardial metabolic disorders due to ischemic heart disease, such as angina or acute myocardial infarction. It is applicable for treating carnitine deficiency in patients with end-stage kidney disease undergoing dialysis. It helps improve metabolic issues related to the heart and kidneys.

How it is given

Adult administration

1. Primary and secondary carnitine deficiency Myocardial metabolic disorder due to ischemic heart disease: angina pectoris, acute myocardial infarction Adults: Administer 2~3 g of L-carnitine daily in 2~3 divided doses by intramuscular or intravenous injection. Adjust the dose as appropriate according to age and symptoms. 2. Treatment of carnitine deficiency in patients with end-stage renal disease undergoing hemodialysis Initially, administer 10~20 mg/kg intravenously over 2~3 minutes at the end of each hemodialysis session. However, the dose may be adjusted according to the plasma L-carnitine level before hemodialysis.

Precautions

When using ampoule containers made of glass, care must be taken as glass fragments may mix in when cutting the container. Extra caution is needed when administering to children and the elderly. This medication should not be used in patients with an allergic reaction to it. Temporary nausea or vomiting may occur during use, and rarely changes in body odor or gastritis may appear. Additionally, in patients with a history of seizures, seizures may occur more frequently or worsen, so caution is required. Various side effects have been reported in chronic dialysis patients, including abdominal pain, allergic reactions, headaches, infections, and pain at the injection site. Cardiovascular issues such as arrhythmias or blood pressure changes may occur, and gastrointestinal issues like loss of appetite, diarrhea, nausea, and vomiting may appear. Furthermore, various side effects have been reported in multiple systems including the blood and lymphatic system, endocrine system, musculoskeletal system, nervous system, respiratory system, and skin system, hence if any abnormal symptoms arise, medical consultation should be sought immediately. The safety of this medication during pregnancy has not been established, so it should only be used in pregnant women or women who are possibly pregnant if the benefits of treatment are deemed greater than the risks. It is unknown how much of this medication is excreted in breast milk during breastfeeding, but since most medications can be transmitted through breast milk, it should be used cautiously.

Side effects

  • Temporary zones
  • vomiting
  • body odor
  • gastritis
  • seizures
  • abdominal pain
  • accidental injury
  • allergic reactions
  • asthma
  • back pain
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  • chest pain
  • fever
  • flu-like syndrome
  • headache
  • infections
  • injection site reactions
  • pain
  • arrhythmia
  • ventricular fibrillation
  • cardiovascular diseases
  • abnormal electrocardiogram
  • bleeding
  • high blood pressure
  • low blood pressure
  • palpitations
  • tachycardia
  • blood disorders
  • anorexia
  • constipation
  • diarrhea
  • dyspepsia
  • gastrointestinal diseases
  • bloody stools
  • gastrointestinal inertia
  • parathyroid diseases
  • anemia
  • hypercalcemia
  • hyperkalemia
  • hypervolemia
  • peripheral edema
  • weight loss
  • weight gain
  • leg cramps
  • myalgia
  • anxiety
  • depression
  • dizziness
  • drug dependence
  • tension increase
  • insomnia
  • sensory abnormalities
  • vertigo
  • bronchitis
  • increased cough
  • dyspnea
  • pharyngitis
  • respiratory diseases
  • rhinitis
  • sinusitis
  • pruritus
  • rash
  • amblyopia
  • eye diseases
  • taste abnormalities
  • urinary tract infections
  • renal failure
  • urticaria
  • facial edema
  • myasthenia gravis

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container that blocks light, at a temperature between 1 degree and 30 degrees Celsius at room temperature. Proper storage maintains the efficacy and safety of the medication.

Appearance and packaging

Appearance

A clear colorless to pale yellow liquid contained in a brown transparent glass ampoule.

Package unit

5 mL/ampoule X 25 ampoules

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.