Medication info
Twinspin Tablet 80/5mg

Twinspin Tablet 80/5mg

Prescription medication경구
Ingredient · strength
Telmisartan›80mg / 1 tabletAmlodipine Besylate›6.935mg / 1 tablet
Manufacturer / importer
(주)바이넥스
Appearance
White to yellowish and light blue double convex oval tablet
Packaging
30 tablets/box [10 tablets/PTP × 3]
Approval status
Active

MFDS item code 201605846 · Approved 2016.09.30 · Insurance code 643104200

Summary

Main use
Improvement of blood pressure control in essential hypertension with the combination of amlodipine or telmisartan
Who takes it
Adults · Children
Adult dose
The recommended dosage for this medication is 1 tablet once daily, taken with water regardless of meals. Taking it at the same time every day (e.g., in the morning) is advisable. For patients with severe renal impairment, treatment should start at a lower dose, and the dose should be gradually increased. Patients with liver impairment should not exceed a daily dose of 40 milligrams of telmisartan. Elderly patients should follow the usual amlodipine dosage, but caution is advised when increasing the dose.
Child dose
Safety and efficacy for pediatric patients under 18 years of age have not been established, thus use of this medication is not recommended.

Ingredients

Manufacturer
(주)바이넥스

Efficacy & effects

Improvement of blood pressure control in essential hypertension with the combination of amlodipine or telmisartan

  • Essential hypertension
View approved original text

For patients with essential hypertension, if blood pressure is not adequately controlled with either amlodipine or telmisartan monotherapy, this medication can be used in combination to assist with blood pressure management. These drugs play a crucial role in lowering blood pressure and protecting cardiovascular health through different mechanisms of action. Proper management of hypertension can contribute to the prevention of serious complications such as stroke or myocardial infarction. Therefore, it is effectively used for blood pressure control in essential hypertension.

How to take

Adult dose

The recommended dosage for this medication is 1 tablet once daily, taken with water regardless of meals. Taking it at the same time every day (e.g., in the morning) is advisable. For patients with severe renal impairment, treatment should start at a lower dose, and the dose should be gradually increased. Patients with liver impairment should not exceed a daily dose of 40 milligrams of telmisartan. Elderly patients should follow the usual amlodipine dosage, but caution is advised when increasing the dose.

Child dose

Safety and efficacy for pediatric patients under 18 years of age have not been established, thus use of this medication is not recommended.

Precautions

This medication should not be taken by women who are pregnant, especially in the second and third trimesters, as it can cause serious harm to the fetus. This drug should not be administered to patients with certain conditions, such as severe liver disease, severe hypotension, cardiogenic shock, or unstable heart failure following acute myocardial infarction. Additionally, women with allergies to any components of this drug or who are breastfeeding should avoid taking it. Patients with primary aldosteronism, valve stenosis, liver disease, gastrointestinal disorders, or renovascular hypertension should use this medication with special caution. In elderly patients, the dose should be adjusted carefully, and patients with reduced kidney function should frequently monitor their kidney status through blood tests. This medication may cause side effects like dizziness, peripheral edema, or hypotension, and in severe cases, fainting or heart-related issues may occur, so if symptoms arise, it is essential to consult a healthcare professional immediately. There may be instances of significantly low blood pressure or worsening kidney function, thus regular blood pressure and blood tests are necessary. This drug may interact with other medications; therefore, it is crucial to inform the healthcare provider, especially if taking diuretics, potassium supplements, lithium, digoxin, warfarin, or non-steroidal anti-inflammatory drugs. If pregnancy is confirmed, it is necessary to discontinue this medication as soon as possible and switch to other treatment options. It is also safe not to take this medication while breastfeeding. Caution is needed when driving or operating machinery as dizziness or drowsiness may occur. In case of overdose, severe hypotension, dizziness, or heart problems may arise, and immediate emergency treatment is required. This medication is not recommended for children as safety and efficacy have not been established.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), cold sweat, pallor, severe allergic reaction, severe rash, blisters, peeling skin, pain in oral/ocular mucosa, severe skin adverse reactions, difficulty breathing or shortness of breath, asthma attack, respiratory issues along with cough and fever, difficulty breathing, yellowing of the skin or eyes (jaundice), profound malaise, liver dysfunction (jaundice), sudden and severe headache, lightning headache, seizures, loss of consciousness

Mild side effects

  • Dizziness
  • peripheral edema
  • upper respiratory infection
  • pharyngitis
  • sinusitis
  • urinary tract infection
  • cystitis
  • anemia
  • hyperkalemia
  • hypoglycemia
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  • hyponatremia
  • hyperglycemia
  • depression
  • insomnia
  • anxiety
  • confusion
  • drowsiness
  • migraine
  • paresthesia
  • tremor
  • visual disturbances
  • vertigo
  • tinnitus
  • palpitations
  • bradycardia
  • tachycardia
  • flushing
  • hypotension
  • orthostatic hypotension
  • cough
  • abdominal pain
  • dyspepsia
  • nausea
  • vomiting
  • dry mouth
  • liver function abnormalities
  • pruritus
  • rash

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light and should be stored in a container that does not allow light to enter. Furthermore, the drug should be stored at a temperature between 1 to 30 degrees Celsius, which is normal room temperature, avoiding places that are too hot or too cold.

Appearance and packaging

Appearance

White to yellowish and light blue double convex oval tablet

Package unit

30 tablets/box [10 tablets/PTP × 3]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.