Twintera Tablet 40/5 mg

Adult dose

The recommended dose of this drug is one tablet once daily, taken with water regardless of meals. It is advised to take it at the same time each day (e.g., in the morning). For patients with renal impairment, dose adjustment is not necessary for mild to moderate renal impairment; however, for severe renal impairment, treatment should start at a lower dose and be increased gradually. For patients with liver impairment, telmisartan should not exceed 40 mg per day.

Child dose

The safety and efficacy of this drug have not been established in pediatric patients under 18 years old, thus its use is not recommended.

This drug should not be used during pregnancy, especially in the second and third trimesters, as it can cause serious risks to the fetus. Patients with hypersensitivity to this drug, those who are pregnant or breastfeeding, patients with severe liver or heart problems, patients in severe hypotension or shock, and patients with unstable heart failure after acute myocardial infarction should not take this drug. Particular caution is needed when prescribing this drug to patients with primary aldosteronism, certain cardiac valve diseases, liver impairment, gastrointestinal diseases, renal artery stenosis, dialysis patients, and the elderly. While taking this drug, side effects such as dizziness or peripheral edema may commonly occur, and in rare cases, symptoms such as syncope or cardiac irregularities may appear. The use of this drug should be avoided during pregnancy, and if pregnancy is confirmed, it should be discontinued immediately and alternative safe treatment should be initiated. Due to the risk of hypotension, patients with fluid or salt depletion should stabilize their condition before taking this drug, and if symptoms of hypotension occur, they should receive appropriate treatment immediately. As blood potassium levels may rise, caution is required when taking potassium supplements or medications containing potassium. Patients with impaired kidney function should regularly check renal function and electrolyte status through blood tests. Patients with heart disease should be cautious as the use of this drug may increase the risk of angina or myocardial infarction. This drug can cause drowsiness or dizziness, so caution is needed when driving or operating machinery. There may be interactions with other medications, so it is important to consult a specialist when used in combination, especially with digoxin, lithium, warfarin, non-steroidal anti-inflammatory drugs, and grapefruit juice. In cases of overdose, symptoms such as hypotension, changes in heart rate, dizziness, and acute renal failure may occur, thus requiring immediate medical attention for appropriate treatment. This drug is not recommended as its safety and efficacy have not been established for children. Elderly patients should adjust the dose and increase it gradually for safety.

Serious side effects

Urticaria, angioedema, angioedema (accompanied by fatal outcomes), toxic epidermal necrolysis, Stevens-Johnson syndrome, photosensitivity reactions, thrombocytopenia, leukopenia, anaphylactic reactions, sepsis (including fatal outcomes), hepatitis, jaundice, liver dysfunction, vasculitis, dyspnea, interstitial lung disease, renal impairment (including acute renal failure), syncope, myocardial infarction, ventricular tachycardia, arrhythmia, atrial fibrillation, and severe systemic hypertension.

Mild side effects

• Dizziness
• peripheral edema
• syncope
• drowsiness
• headache
• paresthesia
• taste disturbance
• tremor
• visual impairment
• dizziness

This drug is sensitive to light, so it should be stored in a container that does not allow light in and at room temperature between 1 and 30 degrees Celsius. This will help maintain the drug's efficacy and prevent degradation.

Appearance

This is a white and light gray, double-convex oval tablet.

Package unit

30 tablets (10 tablets/PTPX3)