Enpistar Tablets 40/5mg

Adult dose

The recommended dosage is one tablet once a day, to be taken with water regardless of meals. It is recommended to take it at the same time every day (e.g., in the morning). For patients with renal impairment, no dose adjustment is necessary for mild to moderate cases, but for severe renal impairment, it is advised to start with a lower dose and gradually increase. For patients with liver impairment, the daily dosage should not exceed 40 milligrams. Elderly patients (75 years old and over) should start treatment with smaller doses and increase gradually, and their condition monitored carefully.

Child dose

Safety and efficacy have not been established in patients under 18 years of age, so the use of this medication is not recommended.

This drug may pose serious risks to the fetus or newborn during pregnancy, especially in the second and third trimesters, and should not be taken by women who are pregnant or may become pregnant. People allergic to the active ingredients or similar substances, those with severe liver impairment, hypotension, or heart function issues should not take this medication. Patients with impaired liver or kidney function, the elderly, or patients with certain heart diseases should use this drug more cautiously and be monitored carefully according to a physician's instructions. When taking this medication, side effects such as dizziness, swelling, or hypotension may occur; if symptoms are severe, immediate consultation with a healthcare professional is necessary. It is crucial to monitor blood pressure and heart conditions regularly during treatment, especially since the medication can lower blood pressure too much or cause heart problems. This drug may interact with other medications, so inform your doctor or pharmacist about any current medications you are taking. Women who are pregnant or breastfeeding should not take this medication and should stop taking it immediately and consult a physician if pregnancy is planned or confirmed. The safety and efficacy have not been established for use in children, so its use is not recommended in this age group. In case of overdose, there is a risk of hypotension, dizziness, or heart function decline, requiring immediate medical attention.

Serious side effects

Severe allergic reactions (urticaria, angioedema), severe skin reactions (angioedema, urticaria, Stevens-Johnson syndrome), respiratory issues (dyspnea), liver abnormalities (jaundice), severe neurological symptoms (syncope), severe edema or urination abnormalities (kidney dysfunction, acute renal failure), sepsis, leukopenia, thrombocytopenia, anaphylactic reactions, myocardial infarction, ventricular tachycardia, arrhythmias, atrial fibrillation, vasculitis, hepatitis, jaundice, liver dysfunction.

Mild side effects

• Dizziness
• peripheral edema
• upper respiratory tract infection
• urinary tract infection
• anemia
• hyperkalemia
• depression
• insomnia
• anxiety
• drowsiness

This medication is sensitive to light and should be stored in a special container that does not allow light in. Additionally, it should be stored at room temperature, between 1 to 30 degrees Celsius, away from extremes of heat or cold to maintain effectiveness.

Appearance

This is a biconvex, oval double tablet that is white and light gray.

Package unit

30 tablets (10 tablets/PTPX3)