Telmidipine 40/10 mg Tablet

Adult dose

Take 1 tablet once daily, with water regardless of meals. It is advised to take it at the same time daily (for example, in the morning). Patients with kidney impairment do not need dosage adjustment for mild to moderate impairment, but severe kidney impairment patients should start with a lower dose and gradually increase. Patients with liver impairment should not exceed 40 mg daily. Elderly patients (age 75 and older) should start with a lower dose.

Child dose

Safety and efficacy for patients below 18 years have not been established, hence administration is not recommended.

This medication can cause serious harm to the fetus and neonate, especially during the second and third trimesters of pregnancy, thus should not be taken by women who are pregnant or may become pregnant. Additionally, it is contraindicated for patients with an allergic reaction to this medication or with cholestasis, severe liver dysfunction, severe hypotension, or serious heart conditions. Particular caution is needed for patients with impaired kidney function or diabetes, as well as in those with specific heart valve diseases. Dizziness and peripheral edema are common side effects, and rarely syncope or serious heart issues may occur, so if there are any unusual symptoms, immediate consultation with healthcare professionals is required. As this medication lowers blood pressure, hypotension may occur, and monitoring of blood potassium levels is necessary as there is a risk of hyperkalemia. Also, this medication can affect liver and kidney function, so consulting a doctor is essential if there are any liver or kidney disorders. Caution is required when driving or operating machinery as dizziness or drowsiness may occur. This medication may interact with other antihypertensive medications or specific drugs, so it’s crucial to inform the doctor of any other medications being taken. It is advisable not to take this medication while breastfeeding, and it is not recommended for children as safety and efficacy have not been sufficiently established. In the event of overdose, there may be serious hypotension or heart problems, so adherence to the prescribed dosage is crucial, and emergency treatment should be sought if unusual symptoms occur. Finally, this medication should be stored out of reach of children and opened just before administration.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in the mucous membranes of mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, breathing difficulties accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confused consciousness, visual disturbances, paralysis, urination abnormalities

Mild side effects

• Dizziness
• peripheral edema
• upper respiratory tract infection
• urinary tract infection
• cystitis
• anemia
• hyperkalemia
• hypoglycemia
• hyponatremia
• hyperglycemia

This medication is sensitive to light and should be stored in a container that blocks light. Furthermore, it should be kept at room temperature between 1 and 30 degrees Celsius for safe storage.

Appearance

White and light blue, convex, dual-layer oval tablet

Package unit

30 tablets/box [10 tablets/PTP×3]