Nexium Mups 40 mg (Esomeprazole Magnesium Trihydrate)

Adult dosage

This medication should be swallowed with liquids such as water and should not be chewed or crushed. Patients who have difficulty swallowing the tablets can dissolve it in half a cup of non-carbonated water. Other beverages should not be used as they may dissolve the enteric coating. Once dissolved, it should be consumed immediately or within 30 minutes without chewing, and the cup used for the medication should be rinsed with half a cup of non-carbonated water and drunk again. Floating medication particles should not be chewed or crushed during consumption.

Children's dosage

Adolescents 12 years and older follow the same dosage as adults. No experience has been reported for children under 12 years.

This medication should not be administered to patients with specific allergic reactions or a history of allergy to this medication or similar ingredients. Additionally, patients undergoing treatment with certain antibiotics or antivirals, as well as nursing women, should not use this medication. Patients with heart issues or those who have previously had a myocardial infarction should use this medication with caution. While taking this medication, rare but serious blood abnormalities, allergic reactions, neurological issues, gastrointestinal problems, and liver function abnormalities can occur, so symptoms should be closely monitored. Prolonged use of this medication may lead to electrolyte imbalances such as magnesium, calcium, or potassium deficiencies, necessitating regular testing. Due to its acid-reducing effects, this medication may slightly increase the risk of gastrointestinal bacterial infections; therefore, if gastrointestinal symptoms like diarrhea persist, consulting a physician is necessary. Long-term use may increase the risk of fractures, so patients at risk of osteoporosis are recommended to undergo periodic bone density tests. This medication can interact with other drugs; therefore, patients taking certain antibiotics, antivirals, anticoagulants, or anticonvulsants should inform their doctor or pharmacist. There is limited data on the safety of this medication during pregnancy, so caution is advised, and it is best not to take it while breastfeeding. In case of overdose, no specific antidote exists, so treatment should focus on symptom relief and general management. Finally, this medication should be kept out of the reach of children, and it is safer not to transfer it to other containers.

Serious side effects

Urticaria, angioedema, anaphylaxis, shock, hypomagnesemia, severe edema, hepatitis, jaundice, liver failure, encephalopathy, skin and mucous membrane syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell's syndrome), acute generalized exanthematous pustulosis, eosinophilia and systemic symptoms with drug reaction (DRESS syndrome), interstitial nephritis, severe allergic reactions, severe skin adverse reactions, respiratory issues, liver abnormalities (jaundice),

Mild side effects

• Headache
• dizziness
• sensory abnormalities
• drowsiness
• taste disturbance
• blurred vision
• bronchospasm
• abdominal pain
• constipation
• diarrhea

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is important to maintain a storage temperature between 1 degrees and 30 degrees Celsius.

Appearance

Pink rectangular film-coated tablets

Package unit

28 tablets/box [7 tablets/Alu-Alu x 4]