Osmadol Injection (Tramadol Hydrochloride)

Adult administration

As tramadol hydrochloride, administer 50-100mg by intravenous or intramuscular injection, and repeat every 4-5 hours as needed. The maximum daily dosage can be up to 400mg.

This medication can cause seizures if taken in excess of the recommended dosage, so it is very important to adhere to the maximum daily dosage. Additionally, this drug should only be used cautiously in patients with epilepsy or those at risk of seizures when absolutely necessary. 长时间使用可能会导致心理和生理依赖，滥用药物风险较高的患者应在严格监督下短期使用。 Taking this medication with alcohol or central nervous system depressants (e.g., benzodiazepines) can lead to severe sedation, respiratory depression, coma, or even death, so it should be avoided or extremely carefully monitored. Genes may cause some individuals to metabolize this medication more quickly than expected, which increases the risk of respiratory depression, thus requiring dosage adjustment and symptom monitoring. This medication should not be used in children under 12 years of age or adolescents under 18 years of age who have undergone tonsillectomy or adenoidectomy, and adolescents aged 12 to 18 should also avoid it if there are any special risk factors. This drug is not to be administered to patients with acute alcohol intoxication, central nervous system drug intoxication, severe respiratory depression, head injuries or brain lesions, patients taking MAO inhibitors, severe kidney or liver impairment, pregnant or nursing women. When administered, symptoms like nausea, drowsiness, dizziness may occur, so driving or operating dangerous machinery should be avoided. Long-term use may lead to tolerance, requiring higher doses, and sudden cessation may trigger withdrawal symptoms, so dosage should be gradually reduced. This medication can interact with various other drugs, so if other medications are being taken, it is essential to consult with a doctor or pharmacist, especially when used in conjunction with central nervous system depressants, antidepressants, or antipsychotic medications. In case of overdose, serious respiratory depression or seizures may occur, and immediate emergency treatment is essential, with naloxone potentially used as an antidote. This medication should be stored out of the reach of children and kept in its original container to prevent misuse or degradation.

Serious side effects

rash, angioedema, shock, anaphylaxis, bronchospasm, severe swelling, respiratory depression, difficulty breathing, asthma exacerbation, facial pallor, palpitations, vascular dilation, hypotension, arrhythmia, syncope, orthostatic hypotension, tachycardia, hypertension, epileptic seizures, convulsions, severe allergic reactions, severe skin adverse reactions, Stevens-Johnson syndrome, jaundice, elevated liver enzyme levels, acute or chronic adrenal insufficiency symptoms (severe abdominal pain,

Mild side effects

• drowsiness
• dizziness
• unsteadiness
• nausea
• vomiting
• abdominal distension
• abdominal pain
• loss of appetite
• constipation
• thirst

This medication should be stored in a sealed container after use and kept at room temperature between 1 and 30 degrees Celsius. This way, the effectiveness of the drug can be maintained and degradation can be prevented.

Appearance

A colorless, transparent ampoule containing a colorless liquid

Package unit

1ml x 50 ampoules/Box