Rizonel Plus Tablets (Risedronate Sodium 2.5 Hydrate, Colecalciferol Concentrate (Powder Form))

Adult dose

Take 1 tablet of this medication orally once a week. Since food can interfere with the absorption of this medication, it should be taken at least 30 minutes before breakfast or at least 2 hours before or after ingesting food and beverages throughout the day. When taking, it should be swallowed with a sufficient amount of pure water (170–230 mL) in an upright position and not chewed or sucked. Do not lie down for at least 30 minutes after taking the medication.

This medication can irritate the gastrointestinal mucosa, which may cause symptoms such as esophagitis, esophageal ulcers, and esophageal erosion. If you experience symptoms such as difficulty swallowing, pain while swallowing, pain behind the breastbone, or heartburn during treatment, stop taking the medication immediately and consult a doctor. When taking this medication, it is important to take it with a sufficient amount of water (170–230 mL) and to remain upright for at least 30 minutes after taking it. It is crucial to take it at least 30 minutes before or after meals with an interval. Patients with esophageal dysmotility, severe kidney impairment, hypocalcemia, or lactose intolerance should not take this medication. The effectiveness of this drug may be reduced if taken with other medications that interfere with the absorption of calcium and vitamin D, so sufficient time intervals should be maintained between doses. Patients undergoing dental surgery or with oral diseases are at risk of jaw necrosis, so they should consult a doctor before dental treatment and pay special attention to oral hygiene. Use of this medication is not recommended during pregnancy or breastfeeding, and it is necessary to consult a doctor before use. In case of overdose, symptoms of hypocalcemia may occur, so caution is needed, and patients should inform medical personnel immediately if any abnormal symptoms arise. The elderly can generally use this medication safely, but it is advisable to consult a doctor if there are any specific health conditions. During treatment, it is important to consume sufficient calcium and vitamin D along with weight-bearing exercises, and it is advisable to avoid smoking and excessive alcohol consumption.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, fever with severe rash, blisters, skin peeling, pain in oral/eye mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough+fever, yellowing of the skin or eyes (jaundice), severe fatigue, sudden and severe headaches, lightning headaches, seizures, confusion, visual abnormalities, paralysis, urination

Mild side effects

• Back pain
• pain
• abdominal pain
• neck pain
• weakness
• chest pain
• infections
• hypertension
• cardiovascular diseases
• angina

This medication should be stored in a tightly closed container to prevent air and moisture from entering, and it is recommended to store it at room temperature between 1 and 30 degrees Celsius. Storing it this way will help maintain the effectiveness of the medication and ensure safe use.

Appearance

Light orange oval film-coated tablets

Package unit

4 tablets/PTP