Tuberotong 30/5 mg (Pimasartan Potassium, Rosuvastatin)

Adult dose

Pimasartan: Administer 30–60 mg once daily regardless of meals, and if blood pressure is not controlled, the dose may be increased to 120 mg once daily. For patients with renal impairment, start at 30 mg once daily in cases of severe impairment and do not exceed 60 mg. For patients with reduced effective blood volume, the initial recommended dose is 30 mg once daily. Rosuvastatin: Start at 5 mg once daily.

This drug can cause serious harm to the fetus and newborn, especially during the second and third trimesters of pregnancy; therefore, it should be discontinued immediately if pregnancy is confirmed. Women who are allergic to any components of this medicine or are pregnant or may become pregnant, as well as breastfeeding women, should not take this medicine. Patients with severe liver dysfunction, severely impaired kidney function, or specific muscle disorders should not take this medicine. Patients with low blood volume or salt depletion, impaired kidney function, or heart disease should be cautious when taking this medicine and should do so under medical supervision. This medicine can cause muscle-related side effects such as muscle pain, myopathy, and rarely rhabdomyolysis; if any abnormal symptoms in the muscles occur, it is essential to notify medical personnel immediately. Regular liver function tests and blood tests must be performed during treatment, and administration should be stopped if there are any abnormal symptoms in the liver or kidneys. As this medicine may interact with other drugs, it is necessary to inform a doctor or pharmacist, especially when taken in conjunction with potassium-sparing diuretics, lithium, non-steroidal anti-inflammatory drugs, certain antibiotics, antifungals, and immunosuppressants. The safety and efficacy of this drug in children and adolescents under 18 have not been established, and the elderly may be more sensitive to this drug, so caution is needed. Dizziness or drowsiness may occur while driving or operating machinery, so caution is advised. This drug should be kept out of reach of children, and it is recommended to avoid transferring it to other containers.

Serious side effects

• Hives
• hepatitis
• hyperkalemia
• thrombocytopenia
• jaundice
• Stevens-Johnson syndrome
• DRESS syndrome
• rhabdomyolysis
• acute kidney failure
• renal failure

Mild side effects

• Headache
• dizziness
• indigestion
• nausea
• upper abdominal pain
• gastroenteritis
• nasopharyngitis
• tonsillitis
• upper respiratory infection
• fever

This drug should be stored in a tightly closed container to avoid exposure to air or moisture and should be kept at room temperature between 1 to 30 degrees Celsius. Storing it this way helps maintain the effectiveness of the medicine for a longer period.

Appearance

White, convex, octagonal film-coated tablets

Package unit

30 tablets/box [10 tablets/PTP packaging × 3], 100 tablets/box [10 tablets/PTP packaging × 10], 30 tablets/box [10 tablets/Alu-Alu packaging × 3], 100 tablets/box [10 tablets/Alu-Alu packaging × 10]