Tuberon Tablets 60/10 mg (Pimasartan Potassium, Rosuvastatin)

Adult dose

Pimasartan: administer 30 to 60 mg once daily, regardless of meals. If blood pressure is not adequately controlled, the dose can be increased to 120 mg once daily. Rosuvastatin: initial dose is 5 mg once daily, and the maintenance dose can be adjusted to 10 mg once daily. The maximum dose can be increased up to 20 mg once daily. Take at the same time each day if possible.

This medication can cause serious harm to the fetus when taken during pregnancy, especially in the second and third trimesters; therefore, if pregnancy is confirmed, it should be stopped immediately. Individuals with allergic reactions to the components of this medication or who are pregnant or potentially pregnant, as well as nursing individuals, should not take it. It is safe not to take this medication for patients with moderately to severely impaired liver function, biliary obstruction, muscular disorders, or severely impaired renal function. Patients with low blood volume or sodium, impaired kidney function, or certain heart conditions should be closely monitored for risks of hypotension or worsening renal function when taking this medication. This medication may affect liver function, so liver function tests should be performed regularly before and during use, especially for patients with a history of liver diseases. Muscle-related adverse effects such as myalgia, muscle weakness, myopathy, or rhabdomyolysis may occur, so if these symptoms appear, inform a healthcare professional immediately and stop taking the medication. This medication may interact with several other drugs, so if the patient is currently taking other medications, it is essential to inform healthcare professionals, especially when combined with certain antibiotics, immunosuppressants, diuretics, or antihypertensives. Elderly individuals or those with genetic factors may react differently to the medication, so dosage adjustments may be necessary based on age and health status. Dizziness or drowsiness may occur while driving or operating machinery during this medication's use, so caution is advised. Safety and efficacy have not been established in children and adolescents under 18 years, so it is advisable not to use in this age group. This medication should be stored out of reach of children, and it is advisable not to transfer it to another container.

Serious side effects

Acute pancreatitis, bowel obstruction, hemorrhagic duodenal ulcer, appendicitis, acute renal failure, chronic renal failure, nephrolithiasis, pyelonephritis, thrombocytopenia, acute hepatitis, jaundice, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms, immune-mediated necrotizing myopathy, rhabdomyolysis, severe muscle weakness, ocular myasthenia, death, epilepsy, exacerbation of cerebral infarction, cerebral hemorrhage, cerebral infarction, transient ischemic attack, intracranial hemorrhage,

Mild side effects

• Headache
• dizziness
• dyspepsia
• nausea
• fever
• hepatitis
• myalgia
• pruritus
• weakness
• loss of appetite

This medication should be stored in a tightly closed container to prevent air or moisture infiltration and should be kept at room temperature between 1 to 30 degrees Celsius. Proper storage helps maintain the medication's efficacy.

Appearance

Orange convex octagonal film-coated tablets

Package unit

30 tablets/box [10 tablets/PTP packaging ×3], 100 tablets/box [10 tablets/PTP packaging ×10], 30 tablets/box [10 tablets/Alu-Alu packaging ×3], 100 tablets/box [10 tablets/Alu-Alu packaging ×10]