Clovain Duo Capsule

Adult dosage

Administer 1 capsule once daily.

This drug prevents blood from clotting to prevent thrombus formation. However, if you take this medication, bleeding may take longer to stop, so you should notify your doctor immediately if bleeding is severe or persists for a long time. You must inform your healthcare provider about taking this medication before undergoing any surgery or starting a new medication. Genetic variations that affect the function of a specific enzyme (CYP2C19) may reduce the efficacy of this drug and increase the risk of cardiovascular problems, so caution is required. Moreover, interactions with certain medications may alter the drug's blood concentration and increase the risk of bleeding, so it is best to avoid concomitant administration. Individuals who frequently consume alcohol have a higher risk of gastrointestinal bleeding, so it is essential to consult with a doctor or pharmacist before taking this medication. This drug should not be used in patients with a history of gastrointestinal bleeding, hemophilia, severe liver or kidney dysfunction, women in late pregnancy or during breastfeeding, and patients with lactose intolerance. Caution should be exercised when using this medication for patients with a history of gastrointestinal bleeding or bleeding tendencies due to bleeding risks. Patients scheduled for surgery should stop taking this medication 5-7 days prior to the procedure and resume once hemostasis is confirmed. This drug may cause various side effects such as thrombocytopenia, allergic reactions, skin rashes, gastrointestinal disturbances, headache, dizziness, etc., so any abnormal symptoms should be discussed with a healthcare provider immediately. Notably, if bleeding symptoms or severe allergic reactions or blood abnormality symptoms arise, immediate treatment is required. This drug should not be used during pregnancy, especially in the third trimester; in the first and second trimesters, it should be used cautiously according to a doctor's judgment. Breastfeeding women are advised against taking this medication. The safety and efficacy of this drug have not been established for children or adolescents under 18 years of age. This drug does not affect the ability to drive or operate machinery; however, caution is necessary due to bleeding risks. In case of overdose, the risk of bleeding can significantly increase, so the prescribed dosage must be adhered to. Store this medication in a tightly sealed container away from air and moisture, ideally at room temperature between 1°C and 30°C.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe rash with fever, blisters, skin peeling, pain in oral/eye mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, etc.

Mild side effects

• Headache
• dizziness
• abdominal pain
• dyspepsia
• diarrhea
• nausea
• rash
• pruritus
• petechiae
• epistaxis

This medication should be stored in a tightly sealed container to protect from air and moisture. It is best to maintain a storage temperature between 1°C and 30°C.

Appearance

An opaque orange hard capsule containing white and slightly yellow pellets and enteric-coated pellets.

Package unit

100 capsules/bottle, 30 capsules/bottle