Multipoten 5 injections

Adult administration

For use according to physician's prescription, checking plasma trace element levels to guide dose adjustments. For metabolically stable patients receiving parenteral nutrition: Zinc 2.5 to 4mg per day Copper 0.5 to 1.5mg per day Manganese 0.15 to 0.8mg per day Chromium 10 to 15μg per day Selenium 20 to 40μg per day Other: For metabolically stable patients with small bowel fluid loss: additional 12.2mg/L (amount of fluid loss) or 17.1.

Child administration

Pediatric patients - Under 5 years: Zinc 100μg per kg body weight per day Copper 20μg per kg body weight per day Manganese 2 to 10μg per kg body weight per day Chromium 0.14 to 0.20μg per kg body weight per day Selenium per kg body weight per day

This drug should not be used in premature infants or newborns because it contains an ingredient called benzyl alcohol, which can cause life-threatening respiratory problems in premature infants. This drug must not be injected into the vein undiluted. Injecting it undiluted can cause phlebitis (inflammation of the veins). Because it is a hypoosmolar solution, it should only be used when mixed with other medications for injection. Administering it alone can pose problems. If any toxic symptoms appear during administration, the injection should be stopped immediately. Due to the aluminum component in the parenteral nutrition solution, patients with impaired kidney function, especially premature infants with immature kidneys, face a higher risk of toxicity with prolonged use. Although the zinc, copper, manganese, chromium, and selenium included in this drug are in small amounts, adhering to the prescribed dosage is vital to prevent toxic symptoms. Before administration, the physician must accurately assess the patient's condition and the required metabolic dosage, and frequently check the concentration of trace elements in the blood to adjust the dosage as necessary. Patients with impaired kidney function should be cautious as zinc can accumulate in the body. Patients with biliary obstruction should be cautious due to the risk of copper and manganese accumulation in the body. Chromium is mainly excreted through the kidneys and may affect blood glucose control, so diabetes patients should check for interactions with their diabetes medications. When administering selenium to patients with kidney or gastrointestinal issues, the dose should be adjusted, and blood transfusion patients should consider the effects of the transfusion. The safety of administering this drug during pregnancy is not established, so it should be used only when the therapeutic benefits outweigh the risks for women who are pregnant or potentially pregnant. Overdose may present with toxic symptoms such as zinc, copper, chromium, and selenium toxicity, so the prescribed dosage must be strictly followed, and if symptoms occur, healthcare professionals should be informed immediately. This drug must be used strictly according to a physician's prescription, and aseptic conditions should be maintained when added to parenteral nutrition solutions. Before use, check for discoloration or particles in the solution, and do not use it if abnormalities are detected.

Serious side effects

• Hypotension
• pulmonary edema
• jaundice
• decreased urine output
• coma.

Mild side effects

• Sweating
• decreased consciousness
• blurred vision
• tachycardia
• significant hypothermia
• diarrhea
• vomiting
• collapse
• behavioral changes
• progressive wasting

This drug should be stored in a sealed container to prevent air or moisture from entering. The storage temperature should be maintained at room temperature between 15 to 30 degrees Celsius. Storing it this way helps maintain the drug’s effectiveness and safety.

Appearance

A colorless or slightly blue transparent solution in a colorless transparent vial.

Package unit

(10ml/vial)x10