Celecoxib 100 mg Tablets

Adult dose

The minimum recommended dose of this medicine should be adjusted for each patient. It may be administered with or without food. ○ Adults 1. Osteoarthritis (degenerative arthritis) Take 200mg of celecoxib once daily, or divide the dose into 100mg twice daily. 2. Rheumatoid arthritis Take 100mg or 200mg of celecoxib twice daily. 3. Ankylosing spondylitis (AS) Administer 200mg of celecoxib once daily, or divide the dose into 100mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400mg daily. If no effect is observed after 6 weeks of treatment at 400mg daily, other treatment options should be considered. 4. Acute pain and primary dysmenorrhea The recommended initial dose is 400mg of celecoxib, with an additional 200mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200mg twice daily. ○ Patients with hepatic impairment For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may pose a risk of gastrointestinal bleeding for those who consume a lot of alcohol daily, so consultation with a doctor or pharmacist is essential. Individuals with heart or vascular issues or risk factors may experience cardiovascular problems such as myocardial infarction or stroke while taking this medication, thus it should be used at the minimum effective dose for the shortest duration possible. Patients with a history of gastric ulcers or bleeding should use this medication cautiously, as it increases the risk of gastrointestinal perforation, ulcers, and bleeding. Avoid using this medication if allergic to it or if there has been a previous allergic reaction to aspirin or other anti-inflammatory pain relievers, if you have severe liver or kidney dysfunction, are pregnant or possibly pregnant, or are nursing. Patients with compromised liver or kidney function or a history of asthma, hypertension, or heart failure should use this medication cautiously, with close observation of their health status during treatment. If symptoms such as dyspepsia, abdominal pain, black stools, or hematemesis occur during medication, immediate medical attention is required. If symptoms such as chest pain, shortness of breath, or slurred speech arise, seek medical attention immediately. Since this medication is metabolized in the liver, taking it with certain drugs may alter blood concentration, and consulting with a doctor or pharmacist regarding potential interactions with other medications is advised. Women who are pregnant or are planning pregnancy should consult beforehand, as this medication may affect reproductive capacity. Elderly patients may have decreased liver and kidney function, increasing the risk of side effects while taking this medication, hence close monitoring is advised. Regular blood tests and liver and kidney function tests are important to check for abnormalities during medication use. Dizziness or drowsiness may occur after taking this medication, so it is advisable to avoid driving or operating machinery.

Gastrointestinal bleeding, cardiovascular thrombotic reaction, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcer, bleeding, bronchitis, sinusitis, upper respiratory infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle hypertonia, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, bowel perforation, pancreatitis, liver enzyme elevation, itching, rash, urticaria, petechial bleeding, angioedema, alopecia, bullous dermatitis, peripheral edema, facial swelling, influenza-like illness, damage, taste distortion, albuminuria, cystitis, hematuria, dysuria, frequency of micturition, nephrolithiasis, urinary incontinence, urinary tract infection, visual disturbance, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, elevated serum creatinine, increased β2-microglobulin, increased NAG, positive urinary hematuria, positive urinary protein, renal dysfunction, acute renal failure, interstitial nephritis, increased serum sodium, increased serum potassium, elevated BUN, increased CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, elevated creatinine, increased alkaline phosphatase, weight gain, loss of appetite, increased LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthropathy, skeletal abnormalities, myalgia, cervical dystonia, synovitis, tendinitis, myositis, leg cramps, fractures, tendon rupture, pain in various areas, muscle stiffness, decreased hematocrit, increased hemoglobin, petechial bleeding, epistaxis, thrombocytopathy, anemia, thrombocytopenia, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, eosinophilic fasciitis, contact dermatitis, injection site reactions, cutaneous nodules, headache, leg cramps, sensory diminution, migraine, neuralgia, neuropathy, perceptual abnormalities, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, ageusia, back pain, allergy exacerbation, allergic reaction, weakness, chest pain, fluid retention, systemic edema, facial edema, fatigue, lethargy, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, septicemia, sudden death, anaphylaxis-like reaction, angioedema, loss of appetite, increased appetite, depression, neuroexcitability, drowsiness, fatal intracranial hemorrhage, hallucinations, exacerbation of epilepsy, upper respiratory infection, herpes simplex, wound infection, gingivitis, herpes simplex, shingles, bacterial infection, fungal infection, soft tissue infection, viral infection, candidiasis, genital candidiasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic breast disease, thoracic neoplasm, chest pain, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, otalgia, hearing impairment, liver dysfunction, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, liver necrosis, vasculitis, pulmonary embolism, interstitial pneumonia, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms, acute generalized pustular dermatitis, exfoliative dermatitis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, focal segmental glomerulosclerosis, female infertility, chest pain, epistaxis, voice disorders, pneumonia, dyspnea, thirst, ulcerative stomatitis, gastritis, allergy, low back pain, hyperlipidemia, diabetes, weight gain, fractures, arthralgia, RA factor positive, shingles, hearing loss

Store this medication in a tightly closed container to protect it from air and moisture, and keep it at room temperature between 1°C and 30°C.

Appearance

White round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle