Aluna Injection (Sodium Hyaluronate)

Adult administration

Typically, for adults, 1 vial is administered once a week for 3 consecutive weeks into the knee joint cavity or shoulder joint. The frequency of administration should be adjusted according to the symptoms. This medication must be administered under strict aseptic conditions.

This drug should not be used in patients with hypersensitivity to the ingredients. Careful use is required in patients who have had hypersensitivity to other medicines, as well as in patients with liver dysfunction or a history of liver disease. Additionally, since this drug is administered into the joint, caution should be taken if there are skin diseases or infections at the injection site. Rarely, serious allergic reactions such as shock may occur during use, so it is important to closely monitor symptoms and discontinue use immediately if any abnormal symptoms appear and seek appropriate treatment. Hypersensitivity reactions may cause swelling around the face or eyes, rashes, and itching, so if these symptoms occur, discontinue the drug and inform the medical institution. Temporary pain, swelling, redness, and warmth may occur at the injection site, so be cautious of this as well. Symptoms such as nausea, vomiting, and fever may appear, so monitor your physical condition closely. Using this drug directly in inflamed joints may worsen symptoms, so it is preferable to wait until inflammation subsides before use. After administration, stabilizing the joint area can help alleviate pain. If the drug leaks outside the joint, pain may occur, so it must be injected precisely within the joint. Injections must be performed in a sterile manner, and if symptoms do not improve, treatment should be stopped after 3 doses. If fluid accumulates in the joint, it may be necessary to remove the fluid before injection. This drug is not suitable for use in intravenous injections or for ocular administration. A syringe gauge of 22-23 is recommended. Caution is needed as some disinfectants may cause the drug to precipitate. Women who are pregnant or may become pregnant should use this drug cautiously, as its safety has not been established, and it should only be used when the benefits of treatment outweigh the risks. During breastfeeding, it is advisable to avoid nursing, as the drug may pass into breast milk. Its safety in children has not been sufficiently verified, so it should only be used cautiously when necessary. Elderly individuals may have decreased bodily functions, so it should be used more carefully.

Serious side effects

• Urticaria
• swelling (severe edema)
• shock symptoms (frequency unknown).

Mild side effects

Edema (facial, eyelid, etc.), facial erythema, rash, itching, pain (mainly transient pain after administration), swelling, fluid retention, redness, warmth, severe local pressure sensation, nausea, vomiting, fever.

This drug must be stored in a sealed container to prevent exposure to air and light. Additionally, it is important to keep it away from direct sunlight and store it at a cool room temperature, between 1 and 30 degrees Celsius.

Appearance

A colorless, transparent, and viscous liquid contained in a glass vial sealed with rubber stoppers at both ends.

Package unit

3 vials (2.0 mL per vial x 3)/box