Vesicam Tablets 10 mg (Solifenacin Succinate)

Adult dose

The usual recommended dose for adults (including older adults) is 5mg once daily. If necessary, the dose may be increased to a maximum of 10mg once daily. This medicine may be taken with or without food and should be swallowed whole with water. Dosage adjustment is required for the following patients. 1. Patients with renal impairment No dosage adjustment is necessary for patients with mild or moderate renal impairment (creatinine clearance>30ml/min). Use with caution in patients with severe renal impairment (creatinine clearance≤30ml/min), and do not exceed 5mg once daily. 2. Patients with hepatic impairment No dosage adjustment is necessary for patients with mild hepatic impairment. Use with caution in patients with moderate hepatic impairment (Child-Pugh class B), and do not exceed 5mg once daily. 3. Patients taking potent cytochrome P450 3A4 (CYP3A4) inhibitors For patients taking ketoconazole or another potent CYP3A4 inhibitor (e.g., ritonavir, nelfinavir, itraconazole), limit the maximum daily dose to 5mg.

This medication should not be used in patients with certain diseases. For example, those with symptoms of urinary retention, severe gastrointestinal disorders, myasthenia gravis, and glaucoma should not take this medication. Additionally, individuals allergic to this medication or its ingredients should avoid use. Patients undergoing dialysis or those with significantly poor liver and kidney function should also avoid this medication. Caution should be exercised when this medication is used in individuals at risk of bladder outlet obstruction or in patients with decreased gastrointestinal motility. Patients with moderately impaired liver or kidney function should take a limited dose and care should be taken when used with certain strong medications. Common side effects when taking this medication may include dry mouth and constipation, blurred vision or dry eyes. These symptoms are more frequent when taken at high doses. In severe cases, serious side effects such as intestinal obstruction, angioedema, or allergic reactions may occur; therefore, if these symptoms appear, immediate medical attention is required. Caution is needed during driving or operating machinery due to symptoms such as drowsiness or blurred vision. This medication may enhance effects or worsen side effects when taken with other anticholinergic drugs, so consultation with a physician is necessary. Also, when taken with drugs that affect enzymes that break down drugs in the liver, dosage adjustments are required. Women who are pregnant should use this medication cautiously as its safety has not been established, and nursing mothers should avoid it as it may be passed into breast milk. The safety and efficacy of this medication have not been confirmed for children, so it is not used in this age group. In the event of an overdose, immediate medical attention is required, and specific therapeutic drug treatment may be necessary according to symptoms. This medication is known to have a low risk of genetic toxicity or tumor development even with long-term use, but it must always be taken according to a doctor's instructions.

• dry mouth
• constipation
• blurred vision
• urinary retention
• dry eyes
• fecal impaction
• colonic obstruction
• intestinal obstruction
• angioedema
• nausea

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. It is recommended to keep the storage temperature between 1 and 30 degrees Celsius. Storing it this way will help maintain the effectiveness of the medication safely.

Appearance

Bright pink round film-coated tablets

Package unit

100 tablets (10 tablets/PTP*10), 30 tablets/bottle, 100 tablets/bottle