Medication info

Jecelen Injection (Arsenic Acid)

Prescription medicationInjections
Ingredient · strength
Selenious Acid›65.4μg / 1mL
Manufacturer / importer
제이더블유중외제약(주)
Appearance
Colorless and odorless transparent liquid in a colorless and transparent vial injection
Packaging
10mL/vial × 10
Approval status
Active

MFDS item code 201604688 · Notified 2016.07.29

Summary

Main use
Improvement of nutritional status through selenium supplementation
Who uses it
Adults · Children
Adult dosage
Inject 20 to 40 μg of selenium daily during stable metabolic total parenteral nutrition (TPN) (this medication contains 40 μg/mL of selenium).
Children's dosage
Inject 3 μg per kg of body weight daily. Frequently monitor plasma selenium levels for reference during the next dosing.

Ingredients

Manufacturer
제이더블유중외제약(주)

Efficacy & effects

Improvement of nutritional status through selenium supplementation

View approved original text

Supplementing selenium is important when receiving total parenteral nutrition (TPN). Selenium supports antioxidant function and immune function, helping to maintain overall health. It prevents selenium deficiency in TPN patients and protects cells from oxidative stress. Therefore, selenium supplementation during total parenteral nutrition is used to improve the nutritional status of patients and reduce the occurrence of complications.

Dosage and Administration

Adult dosage

Inject 20 to 40 μg of selenium daily during stable metabolic total parenteral nutrition (TPN) (this medication contains 40 μg/mL of selenium).

Children's dosage

Inject 3 μg per kg of body weight daily. Frequently monitor plasma selenium levels for reference during the next dosing.

Precautions

This medication contains selenium and should not be used in patients with selenium toxicity. Toxicity can occur with overdose, so if adverse reactions occur, discontinue use immediately and consult a professional. Direct injection into the peripheral vein can cause phlebitis, so it must be diluted before administration, and mixing is crucial. It should be administered cautiously to patients with poor kidney function or premature infants, as aluminum toxicity can occur with long-term parenteral administration due to aluminum content. Rarely, pain or allergic reactions may occur during injection, so if symptoms develop, stop taking it and consult a professional. If unusual symptoms such as dermatitis, hair loss, or vomiting occur, discontinue use immediately. Before administration, visually inspect the solution for any precipitation or discoloration, and prepare in a sterile condition. Selenium is excreted through the kidneys and digestive tract, so dosage may need to be adjusted in cases of renal function or gastrointestinal disorders. For transfusion patients, consider the selenium amount and continuously monitor blood concentration. Its safety in pregnant or lactating women has not been established, so women of childbearing potential should assess the therapeutic benefits and risks before administration, and those breastfeeding should consider discontinuing the drug or breastfeeding. Chronic symptoms of overdose may include dermatitis, vomiting, hair loss, and metallic taste, while acute toxicity can lead to severe vascular and lung symptoms, requiring prompt treatment. In cases of overdose, gastrointestinal lavage or diuretics may be implemented, and in severe poisoning, dialysis may be necessary. This medication should be kept out of reach of children, used immediately after opening, and not transferred to another container. It should be stored in a dry place at room temperature between 15 and 30 degrees Celsius to maintain its effect for a long time.

Side effects and when to seek care immediately

Serious side effects

  • Hives
  • severe swelling (edema)
  • chest tightness
  • difficulty breathing
  • cold sweat
  • pallor
  • shock
  • internal vascular congestion
  • pulmonary hemorrhage
  • congestion
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  • and edema

Mild side effects

  • Pain at the injection site
  • allergic reactions
  • dermatitis
  • odor during sweating or breathing
  • hair loss
  • restlessness
  • vomiting
  • effects on nail and hair growth
  • oral abnormalities
  • gastrointestinal disturbances
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  • tension
  • depression
  • metallic taste
  • garlic-like smell from the mouth

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container to prevent air or moisture ingress, maintaining a storage temperature of 15 to 30 degrees Celsius. Proper storage will help preserve the medication's effectiveness for a longer period.

Appearance and packaging

Appearance

Colorless and odorless transparent liquid in a colorless and transparent vial injection

Package unit

10mL/vial × 10

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.