Donepezil Tablets 10 mg (Donepezil Hydrochloride Hydrate)

Adult dose

The recommended dose of Donepezil Hydrochloride is 5 mg taken once daily before bedtime. The 5 mg dosage should be administered for 4 to 6 weeks, after which clinical response should be assessed for potential increase up to 10 mg. When increasing to 10 mg daily, attention should be given to gastrointestinal adverse reactions. Women over 85 years of age with low body weight should not exceed 5 mg daily and require careful monitoring.

Child dose

There is no experience with the use in children.

This medication should not be used by patients with hypersensitivity to certain ingredients, pregnant women, or nursing mothers. It should also be avoided in patients who are genetically unable to digest lactose. Patients with heart disease should use this medication cautiously, as it can affect heart rhythm. Patients taking non-steroidal anti-inflammatory drugs or with a history of peptic ulcers should monitor their gastrointestinal condition closely. Patients with a history of asthma or obstructive lung disease should be cautious, as symptoms may exacerbate due to bronchoconstriction and increased mucus secretion. Patients with extrapyramidal disorders such as Parkinson's disease should be administered carefully due to the risk of worsening symptoms. Patients allergic to the yellow dye No. 5 contained in this medication should also exercise caution. This medication can cause various adverse reactions such as severe heart problems, gastrointestinal bleeding, liver dysfunction, seizures, and extrapyramidal disorders; therefore, any abnormal symptoms should be reported to medical personnel immediately. Some patients may commonly experience side effects such as nausea, vomiting, diarrhea, dizziness, and insomnia. During treatment, the patient's condition should be regularly evaluated, and if there is no efficacy or severe side effects, discontinuation may be necessary. This medication can affect the ability to drive or operate machinery, so caution is advised. There may be drug interactions, so it is essential to inform healthcare professionals about any medications being taken. Pregnant or nursing women should avoid using this medication unless absolutely necessary and should consult a specialist. The safety of this medication for children has not yet been established, so it should not be used in pediatric patients. In case of overdose, severe nausea, vomiting, respiratory depression, etc., may occur, and immediate emergency treatment is necessary. This medication should be kept out of the reach of children and should not be transferred to other containers.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, peeling skin, pain in oral/eye mucosa, shortness of breath or difficulty breathing, asthma attacks, cough accompanied by fever and respiratory abnormalities, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and very severe headaches, lightning headaches, seizures, altered consciousness, visual disturbances, paralysis, urination.

Mild side effects

• Loss of appetite
• hallucinations
• agitation
• aggressive behavior
• anxiety
• insomnia
• drowsiness
• increased libido
• talkativeness
• mania

This medication should be stored in a tightly sealed container to prevent air or moisture from entering. It is recommended to maintain a storage temperature between 1 and 30 degrees Celsius. Proper storage will help ensure the medication's effectiveness.

Appearance

Yellow round film-coated tablets

Package unit

30 tablets/bottle