Roxof Tablet (Sodium Loxoprofen Hydrate)

Adult dose

1. For indications 1 and 2: Adults: Sodium loxoprofen (anhydrous) 60 mg taken orally three times a day. For single-dose therapy, take 60-120 mg orally. 2. For indication 3: Adults: Sodium loxoprofen (anhydrous) 60 mg taken orally. Generally, 120 mg is taken twice a day, with a maximum of 180 mg per day. It is advisable to avoid taking on an empty stomach.

This medication may increase the risk of gastrointestinal bleeding in individuals who regularly consume more than three drinks of alcohol daily, so it is essential to consult with a doctor or pharmacist. Those with cardiovascular diseases or risk factors should be observed carefully as there is an increased risk of cardiovascular complications such as myocardial infarction and stroke while taking this medication. This drug can cause serious gastrointestinal problems such as gastrointestinal bleeding, ulcers, and perforation, so it should be used cautiously, especially in elderly patients or those with a history of gastrointestinal diseases. Patients with peptic ulcers, severe blood disorders, severely impaired liver or kidney function, severe heart failure, or allergies to this drug or any of its components should not take this medication. Individuals with a history of gastrointestinal ulcers due to previous use of nonsteroidal anti-inflammatory drugs should use this drug cautiously and have their condition monitored periodically during use. If allergic symptoms such as rash, itching, difficulty breathing, or decreased blood pressure occur during use, discontinue the medication immediately and visit a hospital. This drug can cause nervous system side effects such as drowsiness, dizziness, and headaches, so caution is needed when driving or operating machinery. Regular blood tests and liver and kidney function tests should be performed during long-term use to check for abnormalities. Mixing with other nonsteroidal anti-inflammatory drugs may increase the risk of side effects, so it is advisable not to take them together. This medication can severely affect the fetus if taken during late pregnancy, so it must not be taken in late pregnancy, and should be taken at the minimum dose after consulting with a physician during early or mid-pregnancy. It is safest for breastfeeding women not to take this medication. Elderly patients are at higher risk for gastrointestinal bleeding and other side effects, so special caution is needed when taking this medication. The safety of this drug in children has not been established, so it is advisable not to use it in pediatric patients. While taking this medication, be vigilant for unusual symptoms such as gastrointestinal bleeding, skin abnormalities, or difficulty breathing, and if any unusual symptoms are noticed, discontinue use immediately and consult a healthcare professional. This drug should be kept out of the reach of children and should not be transferred to other containers.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, shock, anaphylaxis-like symptoms, peptic ulcers, perforation, hematemesis, melena, blood in stool, shock, Stevens-Johnson syndrome, toxic epidermal necrolysis, erythema multiforme, acute generalized exanthematous pustulosis, acute renal failure, liver function disorders (jaundice), fulminant hepatitis, liver necrosis, liver failure, dyspnea, asthma attacks, interstitial pneumonia.

Mild side effects

• Rash
• itching
• fever
• abdominal pain
• discomfort in the upper abdomen
• loss of appetite
• nausea
• vomiting
• diarrhea
• constipation

This medication should be stored in a tightly closed container to prevent air or moisture from entering, and it is best to keep it at a temperature between 1 and 30 degrees Celsius at room temperature. Proper storage can help maintain the effectiveness of the medication for a longer period.

Appearance

White round tablet

Package unit

(For domestic use) - 30 tablets/bottle, (For domestic use) - 500 tablets/bottle