Esomeprazole Magnesium 40mg (Esomeprazole magnesium dihydrate)

Adult dosage

This medication should be taken with liquids such as water and should not be chewed or crushed. 1) Gastroesophageal reflux disease (GERD) - Treatment of eosinophilic esophagitis: 40 mg once daily for 4 weeks. If symptoms do not resolve or persist, continue for an additional 4 weeks. - Maintenance therapy for preventing recurrence: 20 mg once daily. - Symptomatic treatment for gastroesophageal reflux disease without esophagitis: 1 day once daily, 20 mg.

Children's dosage

Adolescents aged 12 and over: - For treatment of gastroesophageal reflux disease: 40 mg once daily for 4 weeks. If treatment is ineffective or if symptoms persist, continue for an additional 4 weeks. - For gastroesophageal reflux disease symptoms without esophagitis:

This medication should not be administered to patients with allergies or hypersensitivity to specific ingredients or benzimidazole derivatives. Patients with hypersensitivity to penicillin or macrolide antibiotics should also avoid using this medication. Patients taking certain heart-related medications or antiviral drugs, as well as breastfeeding women, should not use this medication. Rare side effects such as blood cell count reductions, hypersensitivity reactions, and hypomagnesemia may occur when taking this medication, requiring caution. Various symptoms, including headache, dizziness, gastrointestinal disturbances, and skin rashes, may manifest, and in severe cases, consultation with a specialist is recommended. Long-term use requires regular monitoring, and it is important to inform your doctor about potential drug interactions that may alter the effects of other medications. Particularly with antibiotic combinations, it is critical to thoroughly review the instructions, as some medications may be contraindicated or require dosage adjustments when used together. This medication may reduce gastric acidity, which can increase the risk of bacterial infections; therefore, if symptoms of diarrhea persist, it is advisable to consult healthcare professionals. Patients at risk of osteoporosis or fractures should exercise caution when taking this medication over extended periods. Patients with genetic issues such as fructose intolerance should avoid taking this medication, and periodic blood tests are necessary due to the potential for hypomagnesemia with long-term use. Limited data exists on the use of this medication during pregnancy, so pregnant women should consult their doctor before use, and breastfeeding women should avoid taking it. In cases of overdose, no specific antidote exists, so treatment should be symptomatic and general management is required. This medication must be kept out of reach of children and transferring it to other containers can compromise its quality.

Serious side effects

Urticaria, angioedema, anaphylaxis, shock, severe hypomagnesemia, jaundice, liver failure, encephalopathy, Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), rhabdomyolysis, severe allergic reactions, severe edema, acute serious skin reactions, and severe neurological symptoms.

Mild side effects

• Leukopenia
• thrombocytopenia
• agranulocytosis
• pancytopenia
• fever
• peripheral edema
• hyponatremia
• hypomagnesemia
• insomnia
• anxiety

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. It is recommended to maintain a storage temperature between 1°C and 30°C. Proper storage will help preserve the effectiveness and safety of the medication.

Appearance

Pink rectangular film-coated tablet

Package unit

28 tablets (14 tablets/Alu-Alu X2)