Neopezil Tablets 5 mg (Donepezil Hydrochloride Monohydrate)

Adult dose

As Donepezil Hydrochloride, 5 mg once daily at bedtime. If abnormal dreams, nightmares, or sleep disturbances occur, consideration may be given to morning administration. Donepezil's concentration reaches a steady state 15 days after administration, so a dose of 5 mg should be given for 4 to 6 weeks. After evaluating clinical response during this period, the dosage can be increased to 10 mg. If increased to 10 mg per day, care should be taken to monitor for gastrointestinal adverse reactions.

Child dose

No experience of use in pediatrics.

This medication is used to relieve the symptoms of Alzheimer's type dementia, with Donepezil Hydrochloride as the active ingredient. Before using this medication, individuals with an allergy to Donepezil Hydrochloride or any other ingredients in this medication should not take it. Furthermore, it is safe for pregnant women or those who might become pregnant, and nursing mothers, to avoid using this medication. This medication contains lactose, so individuals with genetic issues such as lactose intolerance, lactose deficiency, or glucose-galactose malabsorption should also avoid taking it. Individuals with heart conditions should exercise caution as this medication may slow heart rate or cause arrhythmias. Those taking non-steroidal anti-inflammatory drugs or with a history of peptic ulcers should be monitored closely as gastrointestinal symptoms may worsen. Patients with a history of asthma or obstructive pulmonary disease may also experience worsening of symptoms while taking this medication, thus it should be administered carefully. Patients with Parkinson's disease or similar extrapyramidal disorders should be cautious as their symptoms may worsen. Various side effects, such as dizziness, nausea, vomiting, diarrhea, insomnia, appetite loss, abnormal heart sensation, liver dysfunction, and seizures, may occur during the use of this medication. If serious adverse cardiac reactions or severe allergic reactions occur, it is essential to stop taking the medication immediately and consult healthcare professionals. This medication is not approved for the treatment of other forms of dementia aside from Alzheimer's type and should be administered under the supervision of an experienced physician. Additionally, this medication may affect driving or machinery operation abilities, necessitating caution during initial use or dosage adjustments. This medication is metabolized in the liver, and interactions with certain medications may increase or decrease its effect. Therefore, if other medications are being taken, consultation with a doctor or pharmacist is necessary. Pregnant or nursing women are advised not to use this medication, and if it is necessary to take it, cessation of breastfeeding is recommended. Safety for children has not been established; therefore, it should not be used in pediatrics. In cases of overdose, serious symptoms such as nausea, vomiting, bradycardia, and respiratory depression may occur; therefore, care must be taken not to exceed the dosage, and immediate medical attention should be sought in the event of an overdose. This medication should be stored out of reach of children and not transferred to other containers to maintain the quality of the drug.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, peeling skin, pain in mucous membranes of mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, breathing abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headaches, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, urinary incontinence.

Mild side effects

• Nausea
• vomiting
• diarrhea
• loss of appetite
• headache
• fatigue
• dizziness
• insomnia
• drowsiness
• tremor

This medication should be stored in a tightly closed container that is well ventilated, at room temperature between 1 and 30 degrees Celsius. This will help to maintain the medication's effectiveness over time.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle