New Esopra Tablet 40 mg (Esomeprazole Magnesium Trihydrate)

Adult dosage

This drug should be swallowed with liquids like water and not chewed or crushed. 1) Gastroesophageal reflux disease (GERD) - Treatment of erosive esophagitis: Administer 40 mg once daily for 4 weeks. - Long-term maintenance therapy to prevent recurrence in patients with esophagitis: 20 mg once daily. - Treatment of symptoms of gastroesophageal reflux disease without esophagitis: 20 mg once daily.

Children's dosage

Adolescents aged 12 years and older 1) Gastroesophageal reflux disease (GERD) - Treatment of erosive esophagitis: Administer 40 mg once daily for 4 weeks. - Treatment of symptoms of gastroesophageal reflux disease without esophagitis.

This drug should not be used in patients with known allergies to this drug or its components. Particularly, caution is needed when co-administering this drug with penicillin-type antibiotics or macrolide antibiotics in patients with allergies to these medications. Additionally, it is advisable that patients taking certain heart-related medications or antiviral drugs, and nursing mothers or patients with a history of myocardial infarction do not use this drug. This drug may cause various side effects, with headache, abdominal pain, diarrhea, dizziness, and skin rash being commonly reported. Rarely, hematological abnormalities, liver dysfunction, severe allergic reactions, or muscular problems may occur, so if any unusual symptoms appear, immediate consultation with a healthcare professional is necessary. If taking this drug for an extended period, regular checks to confirm any abnormalities are important. As this drug suppresses gastric acid secretion, it may increase the risk of certain bacterial infections. There may be an increased risk of fractures; therefore, bone health should be regularly monitored in long-term use. Further, this drug is highly likely to interact with other medications, so if taking other drugs, it is essential to inform the healthcare professional. During pregnancy, safety data on this drug are limited, thus it should be used cautiously, and it is recommended to avoid administering this drug while breastfeeding. In case of overdose, since no specific antidote is available, treatment should be provided based on the symptoms, and it must be stored in a place out of reach of children.

Serious side effects

Urticaria, angioedema, anaphylactic reactions, shock, skin peeling, severe rash, blisters, oral/ocular mucosal pain, Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), severe hypomagnesemia, liver failure, encephalopathy, liver abnormalities (including jaundice), severe edema, rhabdomyolysis, severe allergic reactions, severe skin reactions.

Mild side effects

• Headache
• insomnia
• anxiety
• confusion
• depression
• aggression
• hallucinations
• dizziness
• drowsiness
• taste disturbance

This drug should be contained in a sealed container and stored at temperatures between 1°C and 30°C in a cool, dry place, avoiding direct sunlight.

Appearance

Pink round film-coated tablets

Package unit

28 tablets (14 tablets/PTP) x 2, 30 tablets/bottle, 300 tablets/bottle