Medication info
Repizole 30mg (Aripiprazole)

Repizole 30mg (Aripiprazole)

Prescription medicationTablet경구
Ingredient · strength
Aripiprazole›30mg / 1 tablet
Manufacturer / importer
명인제약(주)
Appearance
Pink round tablets
Packaging
30 tablets/bottle, 200 tablets/bottle
Approval status
Active

MFDS item code 201604198 · Approved 2016.07.07 · Insurance code 651904410

Summary

Main use
Treatment of schizophrenia and bipolar disorder (acute mania and mixed episodes)
Who takes it
Adults · Children
Adult dose
Adults with schizophrenia: The recommended initial dose is 10 mg or 15 mg once daily, regardless of meals. The dose can be adjusted within the range of 10-30 mg daily and should not be increased within 2 weeks. Maintenance therapy: For stabilized patients for more than 3 months, administer 15 mg daily. Adults with bipolar disorder: The recommended initial dose is 15 mg once daily as monotherapy or adjunct therapy, which may be adjusted up to 30 mg based on clinical response.
Child dose
Adolescents with schizophrenia (13-17 years): The recommended dose is 10 mg daily, starting with 2 mg on the first day, increasing to 5 mg after 2 days, and then increasing to 10 mg after another 2 days.

Ingredients

Manufacturer
명인제약(주)

Efficacy & effects

Treatment of schizophrenia and bipolar disorder (acute mania and mixed episodes)

  • Acute mania
  • mixed episodes associated with schizophrenia and bipolar disorder
  • Tourette's disorder
View approved original text

This medication is used to treat acute mania and mixed episodes associated with schizophrenia and bipolar disorder. It is also effective in alleviating the symptoms of Tourette's disorder. It is a medication that helps improve symptoms of major psychiatric and neurological disorders.

How to take

Adult dose

Adults with schizophrenia: The recommended initial dose is 10 mg or 15 mg once daily, regardless of meals. The dose can be adjusted within the range of 10-30 mg daily and should not be increased within 2 weeks. Maintenance therapy: For stabilized patients for more than 3 months, administer 15 mg daily. Adults with bipolar disorder: The recommended initial dose is 15 mg once daily as monotherapy or adjunct therapy, which may be adjusted up to 30 mg based on clinical response.

Child dose

Adolescents with schizophrenia (13-17 years): The recommended dose is 10 mg daily, starting with 2 mg on the first day, increasing to 5 mg after 2 days, and then increasing to 10 mg after another 2 days.

Precautions

This medication is used for the treatment of psychiatric disorders, specifically prescribed for depression, schizophrenia, bipolar disorder, etc. During the use of this medication, there may be an increase in suicidal thoughts or behaviors, so close monitoring by a physician is required, especially for children and young adults. Particular attention should be paid during the first few weeks of treatment or when changing dosages to watch for any sudden changes in mood or behavior. Before administering this medication to patients suspected of bipolar disorder, appropriate diagnosis and screening tests are necessary. Rarely, severe side effects such as neuroleptic malignant syndrome may occur, characterized by high fever, muscle rigidity, and changes in mental state, and immediate medical attention should be sought. Prolonged use may result in tardive dyskinesia, which are irreversible abnormal movements, so it is important to adhere to the minimum dosage and treatment duration. Elderly patients with dementia are at increased risk of cerebrovascular accidents such as strokes, and this medication has not been approved for the treatment of dementia-related psychiatric disorders; therefore, it should be used with caution. Patients with diabetes should regularly monitor their blood sugar levels due to the potential for increased blood sugar and worsening diabetes. This medication may increase the risk of thrombosis, so patients with risk factors for thrombosis should discuss it with their physician and take appropriate preventive measures before use. Patients with cardiovascular diseases or a history of hypotension or seizures need to be cautious while taking this medication. This medication may cause drowsiness or dizziness, so caution is advised when driving or operating machinery. While taking this medication, side effects such as dry mouth, constipation, headache, insomnia, anxiety, tremors, muscle rigidity, weight gain, and others may occur. Patients with allergic reactions or lactose intolerance should not take this medication. Should any abnormal symptoms, sudden mood changes, or suicidal thoughts develop during treatment, immediate consultation with a physician is necessary.

Side effects and when to seek care immediately

Serious side effects

Rash, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, shedding of the skin, pain in oral/ocular mucosa, difficulty breathing or shortness of breath, asthma attacks, respiratory distress with cough and fever, yellowing of the skin or eyes (jaundice), severe general fatigue, sudden and severe headaches, lightning-like headaches, seizures, confusion, vision disturbances, paralysis, urinary impairments

Mild side effects

  • Nausea
  • vomiting
  • constipation
  • headache
  • dizziness
  • akathisia
  • anxiety
  • insomnia
  • restlessness
  • drowsiness
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  • fatigue
  • increased appetite
  • nasopharyngitis
  • weight gain
  • hypersalivation
  • blurred vision
  • tremors
  • sedation
  • myalgia
  • musculoskeletal rigidity
  • muscle spasms
  • chest pain
  • weight loss
  • thirst
  • loss of appetite
  • palpitations
  • nosebleeds
  • dry eyes
  • sexual dysfunction
  • stuttering
  • hyperactivity
  • sleep disturbances
  • abnormal sensations
  • numbness
  • hallucinations
  • gastrointestinal disturbances
  • drooling
  • urination

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. It is recommended to maintain the storage temperature between 1 to 30 degrees Celsius.

Appearance and packaging

Appearance

Pink round tablets

Package unit

30 tablets/bottle, 200 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.