Telmis Plus Tablet 40/12.5mg

Adult dose

For patients whose blood pressure is not adequately controlled with Telmisartan alone, take once daily with water, regardless of meals. It is recommended to adjust the dosages of each ingredient separately for individual patients before switching to this fixed combination. When clinically appropriate, direct substitution from monotherapy to this medication may also be considered. - Telmisartan/Hydrochlorothiazide combination 40/12.5mg may be administered to patients whose blood pressure is not adequately controlled with 40mg of Telmisartan. - Telmisartan/Hydrochlorothiazide combination 80/12.5mg may be administered to patients whose blood pressure is not adequately controlled with 80mg of Telmisartan. - Telmisartan/Hydrochlorothiazide combination 80/25mg may be administered to patients whose blood pressure is not adequately controlled with either 80mg of Telmisartan or the combination of 12.5mg Hydrochlorothiazide. Sodium depletion or volume depletion should be resolved before starting this medication. Patients with Renal Impairment No dosage adjustment is necessary for patients with mild to moderate renal impairment. This medication should not be administered to patients with severe renal impairment (creatinine clearance <30mL/min). Periodic monitoring of kidney function is recommended. Patients with Liver Impairment This medication should be administered with caution in patients with mild to moderate liver impairment. The daily dose should not exceed 40/12.5mg. This medication should not be administered to patients with severe liver impairment (see usage precautions 2). Thiazide diuretics should be administered with caution to patients with impaired liver function. Elderly Patients No dosage change is required. Pediatric Patients The safety and efficacy of this medication in children under 18 years of age have not been established.

Child dose

The safety and efficacy of this medication in children under 18 years of age have not been established.

This medication can cause severe harm to the fetus when taken during pregnancy, especially in the second and third trimesters, and should be discontinued immediately upon confirmation of pregnancy. Patients who have an allergy to any of the ingredients in this medication, have specific liver or kidney diseases, or are pregnant or breastfeeding should not take this medication. Elderly patients or those with high potassium levels, poor liver function, or heart diseases should use this medication with caution. The Hydrochlorothiazide component may increase the risk of skin cancer, so exposure to sunlight should be avoided, and skin conditions should be regularly monitored while taking this medication. While taking this medication, symptoms such as dizziness, low blood pressure, or electrolyte imbalances may occur, so immediate consultation with a healthcare provider is necessary if symptoms arise. When taken with other medications for blood pressure control, interactions may occur, so it is essential to follow the doctor's instructions and undergo regular blood tests and kidney function tests. This medication requires caution when driving or operating machinery; if drowsiness or dizziness occurs, avoid hazardous activities. In the case of overdose, symptoms such as low blood pressure, electrolyte imbalance, or dehydration may occur, and emergency treatment should be sought immediately. Safety for use in children has not been established, and it should be stored out of reach of children.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, angioedema (including life-threatening consequences), anaphylactic reaction, shortness of breath or difficulty breathing, pulmonary edema, liver dysfunction/hepatic impairment, jaundice, severe skin reactions (severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa), severe allergic reaction, serious neurological symptoms (syncope, seizure, confusion, visual disturbances,

Mild side effects

• Dizziness
• diarrhea
• cough
• pharyngitis
• sinusitis
• hypokalemia
• hyperuricemia
• hyponatremia
• anxiety
• depression

This medication should be stored in a tightly closed container to protect it from air and moisture. It is recommended to maintain a storage temperature between 1 to 30 degrees Celsius. This will help preserve the drug's effectiveness and safety for a longer duration.

Appearance

An oval tablet composed of two layers, white and pink, with possible pink spots on the white layer.

Package unit

30 tablets (10 tablets/PTP × 3)