Asras Tablets (Loxoprofen Sodium Hydrate)

Adult dose

1. For indications 1 and 2 Adults: Administer 60 mg of loxoprofen sodium (anhydrous) orally three times a day. For single-dose therapy, administer 60-120 mg orally. 2. For indication 3 Adults: Administer 60 mg of loxoprofen sodium (anhydrous) orally. In principle, it can be given twice a day, with a maximum of 180 mg per day. It is preferable to avoid taking it on an empty stomach.

Patients who regularly consume more than three alcoholic drinks a day should consult a doctor or pharmacist before taking this medication. Those who consume large amounts of alcohol have an increased risk of gastrointestinal bleeding when taking this medication. In patients with cardiovascular diseases or risk factors, this medication may increase the risk of cardiovascular thrombosis, myocardial infarction, and stroke; thus, both the doctor and the patient should carefully monitor symptoms. Immediate actions should be taken if cardiovascular symptoms occur. This medication can cause serious gastrointestinal side effects such as gastrointestinal bleeding, ulcers, and perforations, especially in elderly individuals or patients with a history of gastrointestinal disorders. The risk of such side effects increases with prolonged use, necessitating careful monitoring of gastrointestinal symptoms. Patients with a history of peptic ulcers, severe blood disorders, liver dysfunction, kidney impairment, heart failure, those who are allergic to this medication or its ingredients, and those who have previously reacted to aspirin or other non-steroidal anti-inflammatory drugs should not take this medication. Pregnant women in late pregnancy and nursing mothers should also refrain from using this medication. Patients with a history of peptic ulcers or blood, liver, and kidney disorders, the elderly, patients with hypertension, blood coagulation disorders, those taking diuretics or ACE inhibitors, and women in early or mid-pregnancy should use this medication with caution and closely monitor their condition under a doctor's guidance. This medication may cause serious allergic reactions such as urticaria, swelling, shortness of breath, and hypotension; if such symptoms occur, the medication should be immediately discontinued, and medical attention should be sought. Additionally, if symptoms such as peptic ulcer, gastrointestinal bleeding, abdominal pain, nausea, vomiting occur, the medication should be stopped immediately, and a doctor's evaluation should be obtained. Rarely, severe side effects such as liver dysfunction, kidney impairment, blood disorders, respiratory difficulties, and skin rashes may occur, so caution is advised. This medication should not be taken in combination with other non-steroidal anti-inflammatory drugs due to increased risk of side effects. Furthermore, it can interact with specific medications such as antidiabetic agents, antibiotics, ACE inhibitors, anticoagulants, diuretics, lithium, and methotrexate; thus, consultation with a doctor is necessary. During pregnancy, especially in late pregnancy, this medication should not be used, and women of childbearing potential should carefully consider the benefits and risks of treatment. It is also advisable for breastfeeding mothers to avoid this medication. Safety for pediatric use has not been established, and the risk of side effects is higher in the elderly, so usage should be approached with caution. This medication should be kept out of reach of children and should not be transferred to other containers.

Serious side effects

Urticaria, severe swelling (edema), tightness in the chest, difficulty breathing, cold sweat, paleness, peptic ulcer, gastrointestinal bleeding, bleeding from the stomach or intestines, perforation, shock, symptoms resembling anaphylaxis, asthma attacks, angioedema, facial swelling (periorbital swelling, oral swelling), Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell's syndrome), erythema multiforme, acute generalized exanthematous pustulosis, extreme fatigue.

Mild side effects

• Rash
• itching
• fever
• abdominal pain
• discomfort in the stomach
• loss of appetite
• nausea
• vomiting
• diarrhea
• constipation

This medication should be stored in a tightly sealed container to prevent exposure to air and moisture, ideally at room temperature between 1°C and 30°C. Proper storage will help maintain the medication’s effectiveness and prevent deterioration.

Appearance

White round tablet

Package unit

30 tablets/bottle, 300 tablets/bottle