ICELCOC Capsule 100 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted according to the patient and may be administered regardless of meals. ○ Adults 1. Osteoarthritis (degenerative arthritis) Take celecoxib 200 mg once daily or 100 mg twice daily. 2. Rheumatoid arthritis Take celecoxib 100 mg or 200 mg twice daily. 3. Ankylosing spondylitis (AS) Administer celecoxib 200 mg once daily or 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg daily. If no effect is observed after 6 weeks of treatment at 400 mg daily, another treatment method should be considered. 4. Acute pain and primary dysmenorrhea The initial recommended dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may pose a risk of gastrointestinal bleeding when taken by individuals who consume three or more alcoholic drinks daily; therefore, consulting a physician or pharmacist is mandatory. It may increase the risk of serious cardiac issues, such as cardiovascular thrombotic events, myocardial infarction, and stroke, so it should be used at the lowest effective dose for the shortest duration possible, and any cardiovascular symptoms should be reported to healthcare professionals immediately. Severe gastrointestinal issues such as ulcers, bleeding, and perforation can occur, especially in elderly patients or those with a history of gastrointestinal diseases; immediate medical attention is required if symptoms like epigastric pain, black stool, or vomiting blood occur. This medication should not be administered to patients with specific allergies, liver, kidney, or heart disease, pregnant or breastfeeding women, or patients with certain genetic metabolic disorders. Patients with compromised liver or kidney function, hypertension or asthma, heart failure, or elderly individuals should use this medication with caution and undergo regular monitoring of liver and kidney function during treatment. This drug may interact with various medications; patients on other medications must inform their healthcare provider, particularly when using blood pressure medications, anticoagulants, antidepressants, and antibiotics. Women who are pregnant or planning to be pregnant should not take this medication; if taken during pregnancy, it should be stopped immediately, and the patient should consult a physician to avoid harm to the fetus. This medication is not recommended for breastfeeding women; nursing should be discontinued if the medication is taken or if the medication should be stopped. The safety and efficacy of this drug in children and adolescents have not been established, so it should not be administered to patients under 18 years old. Dizziness or drowsiness may occur while taking this medication; therefore, it is advisable to avoid driving or operating machinery. Routine blood tests and liver and kidney function checks should be performed if this medication is taken long-term, and immediate consultation with healthcare professionals should be sought if abnormal symptoms arise. In the event of an overdose, symptoms such as lethargy, nausea, vomiting, and abdominal pain may occur, requiring immediate emergency treatment, as there is no specific antidote. This medication should be stored out of reach of children and should not be transferred to another container.

Gastrointestinal bleeding, cardiovascular thrombotic reaction, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcers, hemorrhage, bronchitis, sinusitis, upper respiratory tract infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle rigidity, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, distension, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, blistering dermatitis, peripheral edema, facial edema, influenza-like illness, injury, headache, leg cramps, sensory impairment, migraine, neuralgia, neuropathy, sensory abnormalities, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, allergic reaction, weakness, chest pain, fluid retention, systemic edema, facial swelling, fatigue, malaise, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactoid reaction, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, hepatic necrosis, cholestasis, cholestatic hepatitis, jaundice, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, minimal change disease glomerulonephritis, menstrual disorders, female infertility, chest pain, thirst, ulcerative stomatitis, gastritis, back pain, hyperlipidemia, diabetes, weight gain, fractures, arthralgia, RA factor positive, herpes zoster, pneumonia, dyspnea, elevated ALT, hearing loss, nosebleeds, speech disorder, laryngitis, pneumonia, hearing loss, ear abnormalities, otalgia, hearing loss, ocular hemorrhage, retinal artery or vein occlusion, renal dysfunction, acute renal failure, interstitial nephritis, elevated serum creatinine, increased β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, elevated serum sodium, elevated serum potassium, increased BUN, elevated CPK, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, elevated creatinine, increased alkaline phosphatase, weight gain, anorexia, elevated LDH, hypoglycemia, hyponatremia, synovial sac, arthralgia, arthropathy, skeletal anomalies, myalgia, cervical dystonia, synovitis, tendonitis, myositis, fractures, tendon rupture, pain in the back, muscle stiffness, decreased hematocrit, increased hemoglobin, petechiae, nosebleeds, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, sarcoidosis, contact dermatitis, injection site reaction, cutaneous nodules, ageusia, albuminuria, cystitis, hematuria, dysuria, pollakiuria, nephrolithiasis, urinary incontinence, urinary tract infection, blurry vision, cataract, conjunctivitis, eye pain, glaucoma, vasculitis, anaphylactic reaction, hallucinations, cerebral hemorrhage, aseptic meningitis, loss of taste, loss of smell

Store this medication in a tightly sealed container to protect it from air and moisture, with an appropriate storage temperature between 15 degrees and 30 degrees Celsius. Proper storage will help maintain the effectiveness of the medication for a longer time.

Appearance

A white capsule with blue stripes containing a white to light yellow powder.

Package unit

30 capsules/bottle, 100 capsules/bottle