Alfural XL Tablets (Alfuzosin Hydrochloride)

Adult dose

The recommended dose is 10mg once daily, taken immediately after the evening meal. Do not chew; swallow whole. When administered as adjunctive therapy to a catheter for acute urinary retention associated with benign prostatic hyperplasia, the recommended dose is 10mg once daily, taken after a meal starting on the first day of catheterization. Take for 2-3 days while the catheter is in place and for 1 day after catheter removal, for a total of 3-4 days.

This medication contains the ingredient alfuzosin and should not be used in certain patients. Patients allergic to alfuzosin or any other component of this medication, those with orthostatic hypotension, patients with severely impaired liver function, patients with significantly reduced kidney function (creatinine clearance less than 30 mL/min), patients with intestinal obstruction, patients already taking other alpha-blockers, and those on strong CYP3A4 inhibitors should not use this medication. Moreover, some patients, particularly those being treated for hypertension, may experience symptoms such as dizziness, fatigue, and sweating due to orthostatic hypotension within a few hours after the first dose. When such symptoms occur, it is necessary to lie down and rest, and extra caution is required, particularly for older patients. These symptoms are generally temporary and do not require stopping the treatment, but patients taking heart disease medications or other antihypertensives should be cautious due to the risk of significant blood pressure drop. Patients with symptoms of orthostatic hypotension or those taking antihypertensives or nitrate medications should be administered this medication cautiously, and it should not be used alone in patients with coronary artery disease. If symptoms of angina pectoris recur or worsen, medication should be discontinued immediately. Additionally, it should be used carefully in patients with congenital or acquired QT interval prolongation or those taking medications that prolong the QT interval. Common side effects may include dizziness, headache, nausea, abdominal pain, constipation, and fatigue, while rare side effects may include skin rash, angioedema, and erectile dysfunction. Moreover, this medication may rarely cause a complication called intraoperative floppy iris syndrome during cataract surgery, so patients planning surgery should inform their doctor. When taking this medication, do not crush or chew the tablets; it should be swallowed whole. Patients with previous experience taking other alpha-blockers should be cautious due to the risk of hypotension. Rarely, priapism (persistent erection) may occur, and patients should be adequately informed about this. This medication may increase the hypotensive effect or drug concentration when taken with certain antihypertensives or strong CYP3A4 inhibitors, so concurrent use should be avoided or done with caution. This medication has no indications for use in pregnant or breastfeeding women, nor is it used in pediatric patients. Patients may experience dizziness or weakness during treatment, so caution is required when driving or operating machinery. In case of overdose, hospitalization may be necessary to maintain a lying position and receive hypotension treatment, and this medication is not removed by dialysis. Finally, keep this medication out of reach of children and do not transfer it to another container for safety.

• Fainting
• dizziness
• headache
• vertigo
• syncope
• tachycardia
• angina
• intraoperative mydriasis syndrome
• upper respiratory tract infection
• bronchitis

This medication may be sensitive to air or moisture; therefore, it should be stored in a tightly closed container. It is best to maintain a storage temperature between 1 and 30 degrees Celsius at room temperature to safely preserve the efficacy of the medication.

Appearance

This medication consists of a three-layer film-coated tablet with two yellow layers sandwiching one white layer, both sides convex.

Package unit

30 tablets/bottle