Medication info
Lowtan Plus Tablets (Olmesartan Medoxomil, Hydrochlorothiazide)

Lowtan Plus Tablets (Olmesartan Medoxomil, Hydrochlorothiazide)

Prescription medicationTablet경구
Ingredient · strength
Olmesartan Medoxomil›20mg / 1 tabletHydrochlorothiazide›12.5mg / 1 tablet
Manufacturer / importer
(주)휴온스메디텍
Appearance
Yellowish red round film-coated tablets
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 201603967 · Approved 2016.06.27 · Insurance code 670401270

Summary

Main use
Treatment for controlling essential hypertension
Who takes it
Adults · Children
Adult dose
Before administering this medication, it is recommended to adjust the dosage of Olmesartan Medoxomil or Hydrochlorothiazide alone; if blood pressure is not adequately controlled, administer 1 tablet once daily regardless of meals. The dosage should be adjusted every 2 to 4 weeks based on the patient's blood pressure response. Elderly patients should start at the lowest dose, and careful consideration should be given to kidney function, cardiac function, comorbid conditions, and concomitant medications when adjusting the dose. Patients with renal failure (creatinine clearance)
Child dose
Safety and efficacy in children have not been established.

Ingredients

Manufacturer
(주)휴온스메디텍

Efficacy & effects

Treatment for controlling essential hypertension

  • Essential hypertension
View approved original text

This medication is effective in treating essential hypertension, particularly in cases where blood pressure cannot be adequately controlled with a single drug. Olmesartan Medoxomil works by relaxing blood vessels, and Hydrochlorothiazide helps to eliminate excess salt and water from the body, thus lowering blood pressure. The combined effects of these two components allow for more stable control of blood pressure. Therefore, this drug is a good treatment option for patients who have difficulty controlling their blood pressure. This medication helps improve hypertension and reduces the risk of cardiovascular disease.

How to take

Adult dose

Before administering this medication, it is recommended to adjust the dosage of Olmesartan Medoxomil or Hydrochlorothiazide alone; if blood pressure is not adequately controlled, administer 1 tablet once daily regardless of meals. The dosage should be adjusted every 2 to 4 weeks based on the patient's blood pressure response. Elderly patients should start at the lowest dose, and careful consideration should be given to kidney function, cardiac function, comorbid conditions, and concomitant medications when adjusting the dose. Patients with renal failure (creatinine clearance)

Child dose

Safety and efficacy in children have not been established.

Precautions

This medication can cause serious harm to the fetus and newborn if taken during the second and third trimesters of pregnancy; it should be discontinued immediately upon confirmation of pregnancy. Patients with allergies to the ingredients in this medication or with certain kidney or liver diseases should not take it. Patients with decreased blood volume, weak kidney function, or liver disease should consult with their doctor before use for careful administration. Due to its blood pressure-lowering effects, dizziness or hypotension may occur in the early stages of treatment, requiring caution. Due to Hydrochlorothiazide, electrolyte imbalances, particularly changes in potassium and sodium levels, may occur, necessitating regular testing. If any allergic reactions such as skin rash, itching, facial swelling, or difficulty breathing occur during treatment, medical personnel should be notified immediately. This medication may interact with other antihypertensives, potassium supplements, or diuretics, so it is essential to inform the healthcare provider of any other medications being taken. Elderly patients, children, and those with specific medical conditions may require dosage adjustments, and safety and efficacy in pediatric patients have not been established. In cases of overdose, symptoms such as hypotension, electrolyte imbalances, and dehydration may occur, necessitating immediate medical treatment. The Hydrochlorothiazide component may react sensitively to sunlight, so long-term exposure to ultraviolet light should be avoided, and caution should be exercised if any skin abnormalities occur. During treatment, caution must be taken when undertaking dangerous tasks such as driving or operating machinery, as dizziness or drowsiness may occur. If pregnant or breastfeeding, consider avoiding this medication and consulting a specialist, especially since it may affect the baby during breastfeeding. If any unusual symptoms occur during treatment, consult medical personnel immediately, and regular blood tests and kidney function tests are essential.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (facial edema, angioedema), chest tightness, difficulty breathing, anaphylactic reaction, paleness, severe rash with high fever, blisters, peeling skin, pain in mouth/eyes mucosa, severe skin reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory problems accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, liver abnormalities (jaundice), sudden and severe

Mild side effects

Nausea, metabolic disorders (hyperuricemia, hyperlipidemia, hyperglycemia), dizziness, upper respiratory infection, headache, urinary tract infection, chest pain, back pain, peripheral edema, abdominal pain, dyspepsia, gastroenteritis, diarrhea, increased AST, increased GGT, increased ALT, increased creatine phosphokinase, arthritis, arthralgia, myalgia, cough, rash, hematuria, weakness, vomiting, hair loss, itching, hives, elevated blood pressure, palpitations, fatigue, drowsiness,

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to protect it from air and moisture. A storage temperature of room temperature between 1 and 25 degrees Celsius is recommended.

Appearance and packaging

Appearance

Yellowish red round film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.