Medication info
Mahakan Tablet 16/5 mg

Mahakan Tablet 16/5 mg

Prescription medicationTablet경구
Ingredient · strength
Candesartan Cilexetil›16mg / 1 tabletAmlodipine Besylate›6.935mg / 1 tablet
Manufacturer / importer
에이치케이이노엔(주)
Appearance
Yellow, double-sided, convex, round film-coated tablet
Packaging
30 tablets (10 tablets/ PTP × 3)
Approval status
Active

MFDS item code 201603937 · Approved 2016.06.24 · Insurance code 640007020

Summary

Main use
Improvement of blood pressure control in essential hypertension
Who takes it
Adults · Children
Adult dose
The recommended dosage is 1 tablet once daily, taken with water regardless of meals. It is recommended to take it at the same time every day (e.g., in the morning). For patients with kidney impairment, an initial dose of 4 mg of Candesartan Cilexetil once daily is recommended, so this medication should not be used as initial treatment. For patients with liver impairment, an initial dose of 2 mg of Candesartan Cilexetil once daily is recommended.
Child dose
The safety and efficacy of this medication have not been established in adolescents and children under the age of 18, so its use is not recommended.

Ingredients

Manufacturer
에이치케이이노엔(주)

Efficacy & effects

Improvement of blood pressure control in essential hypertension

  • Essential hypertension
View approved original text

Used for the treatment of essential hypertension that is not adequately controlled by monotherapy with Candesartan Cilexetil or Amlodipine.

How to take

Adult dose

The recommended dosage is 1 tablet once daily, taken with water regardless of meals. It is recommended to take it at the same time every day (e.g., in the morning). For patients with kidney impairment, an initial dose of 4 mg of Candesartan Cilexetil once daily is recommended, so this medication should not be used as initial treatment. For patients with liver impairment, an initial dose of 2 mg of Candesartan Cilexetil once daily is recommended.

Child dose

The safety and efficacy of this medication have not been established in adolescents and children under the age of 18, so its use is not recommended.

Precautions

This medication can cause serious harm or death to the fetus and newborn if administered to pregnant women, so use should be discontinued immediately upon confirmation of pregnancy. Patients with hypersensitivity to this medication or certain conditions such as severe liver disease, severe kidney disease, or hereditary angioedema should not use this drug. Elderly patients, those with hyperkalemia, liver impairment, hypotension, heart valve disease, and kidney disorders should use this medication with caution. During the use of this medication, adverse reactions such as dizziness, headache, abdominal pain, fatigue, edema, and pruritus may occur, and if symptoms persist or worsen, consulting with a healthcare professional is advised. Especially for patients with impaired kidney function or heart failure, blood pressure, kidney function, and serum potassium levels should be regularly monitored. This medication may interact with other antihypertensives, diuretics, and potassium supplements; inform your doctor or pharmacist if you are taking other medications. Pregnant women or those planning to become pregnant are advised not to take this medication, and breastfeeding women should avoid its use or discontinue breastfeeding. The safety and efficacy of this medication in children and adolescents under the age of 18 years have not been established, and its use is not recommended in this population. In case of overdose, symptoms such as hypotension, dizziness, and tachycardia may appear, and immediate medical attention should be sought. Store this medication out of reach of children and do not transfer it to another container for safety. Caution is advised when driving or operating machinery, as dizziness or lethargy may occur.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain of oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attack, cough with fever associated respiratory distress, yellowing of skin or eyes (jaundice), profound fatigue, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual abnormalities, paralysis, urinary changes

Mild side effects

  • Dizziness
  • headache
  • hemorrhoids
  • gastritis
  • upper abdominal pain
  • colorectal polyps
  • pancreatitis
  • chronic gastritis
  • gastroesophageal reflux disease
  • irritable bowel syndrome
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  • reflux
  • constipation
  • nausea
  • abdominal discomfort
  • headache discomfort
  • anosmia
  • sensory abnormalities
  • increased serum triglycerides
  • palpitations
  • chest discomfort
  • fatigue
  • peripheral edema
  • facial swelling
  • chest pain
  • myalgia
  • arthralgia
  • mucositis
  • limb pain
  • low back pain
  • pruritus
  • rash
  • eosinophilia
  • hearing impairment
  • ocular effects

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air and moisture, so it should be stored in a sealed container. The recommended storage temperature is room temperature between 1°C and 30°C.

Appearance and packaging

Appearance

Yellow, double-sided, convex, round film-coated tablet

Package unit

30 tablets (10 tablets/ PTP × 3)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.