Candesartan HCTZ and Amlodipine Tablets 16/10 mg

Adult dose

The recommended dosage for this medication is 1 tablet once daily, taken with water regardless of meals. It is advisable to take it at the same time each day (e.g., in the morning). In cases where blood pressure is not adequately controlled, appropriate dosages of 8/5 mg, 16/5 mg, or 16/10 mg may be administered based on the dosage of Candesartan Cilexetil and Amlodipine monotherapies. For patients with renal impairment, the initial dose of Candesartan Cilexetil 4 mg once daily is recommended, so it is not advisable to administer this medication in initial treatment.

Child dose

The safety and efficacy in adolescents and children under 18 years of age have not been established; therefore, administration of this medication is not recommended.

This medication can cause serious harm or even death to the fetus and neonate if administered to pregnant women, so it should be discontinued immediately upon confirmation of pregnancy. It should not be used in patients with a history of allergies to this medication, specific liver disorders, kidney disorders, or angioedema, and in pregnant or breastfeeding women. Special caution is required for elderly patients or those with specific health conditions such as hyperkalemia, liver disorders, or hypotension when using this medication. During the use of this medication, side effects such as dizziness, headaches, gastrointestinal disorders, edema, and skin rashes may occur; if symptoms are severe or persistent, consult a doctor. Patients with impaired kidney function or heart failure should regularly monitor blood pressure and kidney function, as well as blood potassium levels while on this medication, and must inform their doctor if taking other medications that may increase the risk. This medication may interact with other antihypertensive agents, potassium-sparing diuretics, and NSAIDs, so if you are taking other medications, inform your healthcare professional. Pregnant or breastfeeding women should avoid using this medication and should discontinue breastfeeding if necessary. The safety and efficacy of this medication have not been established in children or adolescents under 18 years of age; therefore, its use is not recommended. In cases of overdose, symptoms such as severe hypotension, dizziness, and tachycardia may appear, so seek medical attention immediately if suspected. Store this medication out of reach of children and in its original container to maintain its quality.

Serious side effects

Hives, severe swelling, chest tightness, breathing difficulties, cold sweat, pallor, severe rash accompanied by high fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, difficulty breathing or shortness of breath, asthma attacks, respiratory difficulties accompanied by coughing and fever, yellowing of the skin or eyes, overall extreme lethargy, sudden and severe headaches, thunderclap headache, seizures, confusion, visual disturbances, paralysis, significantly reduced urine output,

Mild side effects

• Hemorrhoids
• gastritis
• upper abdominal pain
• colorectal polyps
• pancreatitis
• chronic gastritis
• gastroesophageal reflux disease
• irritable bowel syndrome
• reflux
• constipation

Store this medication in a tightly closed container to protect it from air and moisture and keep it at room temperature between 1 to 30 degrees Celsius.

Appearance

White, round, biconvex film-coated tablets

Package unit

300 tablets/bottle, 30 tablets/bottle