Okodipin Tablets (Amlodipine Besylate)

Adult dose

Administer 5 mg orally once daily as Amlodipine, and may increase to a maximum of 10 mg per day based on the patient's response. Adjust as appropriate for age and symptoms.

This medication should not be used in certain patients. It should not be administered to patients who have had an allergic reaction to this drug or similar medications, nursing women, patients with severe liver dysfunction, severe aortic stenosis, and patients in shock. Additionally, it should be used with caution in patients with severe hypotension, patients with renal failure requiring dialysis, elderly patients, and women who are pregnant or may become pregnant. Various side effects may occur while taking this medication. The most common side effects include flushing, fatigue, swelling, palpitations, dizziness, headaches, drowsiness, abdominal pain, and nausea. Rarely, symptoms such as excessively low blood pressure, vasculitis, neurological symptoms, indigestion, skin rashes, liver dysfunction may occur, so it is important to consult healthcare professionals immediately if any unusual symptoms appear. In patients with heart failure, long-term use of this medication may increase the risk of pulmonary edema, so caution is required. Patients with liver dysfunction may require dosage adjustment as the drug’s half-life in the body may be prolonged. This medication works slowly, so it is not suitable for the treatment of acute heart conditions. It is known to have little effect on driving or machine operation ability. This medication may interact when used with other drugs, especially when combined with certain antibiotics, antihypertensives, grapefruit juice, etc. Its safety during pregnancy has not been established, so it should only be used in special cases, and it is recommended to avoid use while breastfeeding. It is only approved for use in children over 6 years old, and its efficacy and safety have not been confirmed in younger children. In the case of an overdose, dangerous conditions such as very low blood pressure and rapid heartbeat may occur, necessitating immediate emergency treatment. There is no evidence linking this medication to an increased risk of cancer or genetic mutations, and no specific issues have been reported with long-term use. Therefore, it is essential to take this medication strictly as directed by a physician and consult a specialist promptly if any adverse reactions or special circumstances arise.

Serious side effects

• Hives
• severe swelling (edema)
• difficulty breathing
• angioedema
• toxic epidermal necrolysis
• hepatitis
• jaundice
• worsening of heart failure
• severe hypotension
• shock

Mild side effects

• Flushing
• fatigue
• swelling
• palpitations
• dizziness
• headaches
• drowsiness
• abdominal pain
• nausea
• weakness

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is best to maintain a storage temperature between 1 and 30 degrees Celsius.

Appearance

White octagonal tablets

Package unit

30 tablets/bottle, 300 tablets/bottle, 500 tablets/bottle