Bivocone Rabeprazole Tablets 20mg (Rabeprazole Sodium)

Adult dose

Gastric ulcer, duodenal ulcer: 10 mg orally once daily. Depending on symptoms, 20 mg may be taken orally once daily. Erosive or ulcerative gastroesophageal reflux disease: 10 mg or 20 mg once daily for 4-8 weeks. If not resolved after 8 weeks of proton pump inhibitor (PPI) treatment, an additional 10 mg or 20 mg may be taken orally twice daily for 8 weeks.

This medication should not be used in patients with allergies or hypersensitivity reactions to specific components or benzimidazoles. Furthermore, when used in combination with amoxicillin or macrolide antibiotics for Helicobacter pylori eradication, patients allergic to these antibiotics should also not be administered this medication. It is also safer for women during pregnancy or breastfeeding not to use this medication. Patients with impaired liver function or elderly patients should use this medication with extra caution, and those with a history of drug allergies should also be administered with care. If allergic reactions such as skin rashes or itching occur while taking this medication, it should be stopped immediately. Regular blood tests are necessary since there can be changes in red blood cell or white blood cell counts. Liver function tests should also be performed regularly, and if symptoms of hepatitis or jaundice appear, the medication should be stopped immediately. Caution is needed as heart-related issues, abnormal blood pressure, headache, and fainting may occur. Gastrointestinal symptoms may include diarrhea, constipation, abdominal pain, and nausea, and in severe cases, consultation with medical staff is required. Neuropsychiatric symptoms may include headache, insomnia, dizziness, and depressive mood, requiring careful observation. If respiratory symptoms such as cough or difficulty breathing occur, medical staff should be informed immediately. Symptoms such as muscle pain, joint pain, skin rash, hair loss, and sweating have also been reported. Eye-related problems may manifest as blurred vision or tinnitus, so consultation with a specialist is required if visual disturbance is felt. There may also be symptoms of urinary tract abnormalities, so if there are difficulties in urination or hematuria, inform medical staff. Long-term use of this medication may increase the risk of fractures related to osteoporosis, thus periodic examinations are necessary for long-term medication. Rarely, hypomagnesemia may occur, so for long-term use or when used in conjunction with certain drugs, magnesium levels in the blood should be checked regularly. This medication strongly suppresses gastric acid secretion, thus there may be a slight increase in the risk of bacterial infection in the gastrointestinal tract; if diarrhea persists, consult medical staff. Caution is needed as drowsiness may occur while driving or operating machinery. There could be interactions with other medications, so especially if taking warfarin, methotrexate, antibiotics, or antiviral drugs, it is crucial to inform medical staff. Pregnant or breastfeeding women should not use this medication, and safety for children has not been established. It is important to take the medication as directed, without chewing or crushing the tablets, but swallowing them whole. Keep it out of reach of children and do not transfer it to another container. If abnormal symptoms appear while taking this medication, it is essential to consult with medical staff for appropriate measures.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, fulminant hepatitis, liver dysfunction, jaundice, interstitial nephritis (which can progress to renal failure), toxic epidermal necrolysis (Lyell's syndrome), Stevens-Johnson syndrome (severe allergic reactions), angioedema, anaphylactic reactions, shock, severe skin adverse reactions, respiratory difficulties, asthma attacks, cough + fever accompanied respiratory abnormalities, sudden death

Mild side effects

• Rash
• itching
• decreased red blood cells
• decreased white blood cells
• increased white blood cells
• increased eosinophils
• increased neutrophils
• decreased lymphocytes
• anemia
• petechiae

This medication may be sensitive to air and moisture, so it must be stored in a tightly sealed container. Avoid storing it in extremely hot or cold places, and it is safe to keep it at room temperature between 1°C and 30°C.

Appearance

Yellowish round enteric film-coated tablets

Package unit

28 tablets (14 tablets/Alu-Alu x 2)