Ezetimibe/Simvastatin Tablet 10/10

Adult dose

This medication is taken once daily in the evening regardless of meals. The dosage range for patients with primary hypercholesterolemia is 10/10mg to 10/40mg daily, with the generally recommended starting dosage being 10/20mg daily. Patients with less need for LDL-cholesterol reduction may start with 10/10mg daily. After adjusting the dose, lipid levels should be checked with an interval of at least 4 weeks to modify the dosage.

This medication can cause serious muscle disorders such as myopathy or rhabdomyolysis, so if muscle pain or weakness symptoms occur, you must notify your doctor immediately. This medication should not be administered to patients with certain liver conditions or abnormally high liver enzyme levels. Pregnant or nursing women should not take this medication, and women who could become pregnant must confirm their pregnancy status before use. This medication may increase the risk of side effects when taken with certain strong drugs, so consult your physician or pharmacist if you are taking other medications. Elderly patients or those with reduced kidney function require extra caution when taking this medication and should have regular blood tests to check liver and muscle health. If any muscle-related adverse symptoms appear, you should discontinue use immediately and consult healthcare professionals, especially since the risk of muscle side effects increases with higher dosages of this medication. While taking this medication, limit alcohol intake, and inform your doctor if there are changes in your health status. Also, this medication may not be suitable for patients with certain genetic metabolic disorders, so if you have a history of drug allergies or adverse reactions, be sure to inform your healthcare provider. This medication is only used in children with restrictions and should be taken in adolescents under medical supervision. Finally, when receiving a new prescription from another doctor while taking this medication, be sure to inform them that you are currently taking this medication.

Serious side effects

• Hives
• severe swelling (angioedema)
• chest tightness
• difficulty breathing
• cold sweat
• paleness
• severe rash with high fever
• blisters
• skin peeling
• pain in oral/ocular mucosa

Mild side effects

Headache, diarrhea, influenza, upper respiratory tract infection, myalgia, limb pain, fatigue, nausea, abdominal pain, constipation, dyspepsia, flatulence, vomiting, pruritus, facial swelling, edema, thirst, increased creatine phosphokinase (CPK) levels, weight loss, dizziness, paresthesia, insomnia, sore throat, nocturia, hematuria, weakness, cataract progression, alopecia, gynecomastia, reduced libido, sexual dysfunction, anemia, HbA1c and fasting blood glucose

This medication is sensitive to air and moisture, so it must be stored in a tightly closed container. It is best to maintain a storage temperature between 1 to 30 degrees Celsius.

Appearance

A white to pale yellow, bidirectional convex, rectangular tablet

Package unit

30 tablets (10 tablets/PTPX3)