Medication info
Belpran Tablet 10 mg (Rabeprazole Sodium)

Belpran Tablet 10 mg (Rabeprazole Sodium)

Prescription medicationTablet경구
Ingredient · strength
Rabeprazole Sodium›10mg / 1 tablet
Manufacturer / importer
(주)인트로바이오파마
Appearance
Pale yellow round enteric-coated tablet
Packaging
28 tablets/Alu-Alu (14 tablets/Alu-Alu*2)
Approval status
Active

MFDS item code 201603764 · Approved 2016.06.22 · Insurance code 052400200

Summary

Main use
Relief of symptoms of gastric ulcers and gastroesophageal reflux disease and effectiveness of combination therapy with antibiotics
Who takes it
Adults
Adult dose
Gastric ulcer, duodenal ulcer: The usual adult dose is 10 mg taken orally once a day, with the possibility of increasing to 20 mg once a day depending on symptoms. The duration of treatment for gastric ulcers is up to 8 weeks, and for duodenal ulcers up to 6 weeks. Erosive or ulcerative gastroesophageal reflux disease: Administer 10 mg or 20 mg once daily for 4 to 8 weeks. If not resolved after 8 weeks, an additional 10 mg or 20 mg can be taken orally twice a day for another 8 weeks.

Ingredients

Manufacturer
(주)인트로바이오파마

Efficacy & effects

Relief of symptoms of gastric ulcers and gastroesophageal reflux disease and effectiveness of combination therapy with antibiotics

  • Gastric ulcer
  • duodenal ulcer
  • erosive gastroesophageal reflux disease
  • ulcerative gastroesophageal reflux disease
  • symptoms of gastroesophageal reflux disease
  • digestive ulcers infected with Helicobacter pylori
  • Zollinger-Ellison syndrome
View approved original text

This medication is used to treat gastric and duodenal ulcers, and to relieve the symptoms of erosive or ulcerative gastroesophageal reflux disease. It also helps in the long-term maintenance therapy for gastroesophageal reflux disease. For patients with digestive ulcer infections caused by Helicobacter pylori, it is treated in combination with antibiotics and is also used in the treatment of the rare Zollinger-Ellison syndrome. This medicine is effective in improving the health of the stomach and esophagus and relieving symptoms, thereby enhancing the quality of life of the patient.

How to take

Adult dose

Gastric ulcer, duodenal ulcer: The usual adult dose is 10 mg taken orally once a day, with the possibility of increasing to 20 mg once a day depending on symptoms. The duration of treatment for gastric ulcers is up to 8 weeks, and for duodenal ulcers up to 6 weeks. Erosive or ulcerative gastroesophageal reflux disease: Administer 10 mg or 20 mg once daily for 4 to 8 weeks. If not resolved after 8 weeks, an additional 10 mg or 20 mg can be taken orally twice a day for another 8 weeks.

Precautions

This medicine should not be used in patients who are allergic to specific drugs or ingredients. It should be avoided especially in cases of hypersensitivity to this medicine or to benzimidazoles, penicillin-class antibiotics, and macrolide antibiotics. Additionally, it is safer not to use this medication in pregnant or breastfeeding women. Caution is necessary for patients with impaired liver function or elderly patients, and those with a history of drug allergies. This medication can cause allergic reactions such as skin rash, hives, and itching, so usage should be stopped immediately if these symptoms occur. Blood tests may reveal anemia, leukopenia, or hepatic dysfunction, necessitating regular check-ups. Various side effects such as cardiac issues, gastrointestinal symptoms, neurological disturbances, respiratory problems, musculoskeletal pain, dermatological abnormalities, visual and auditory disturbances, and urinary tract issues can occur, so medical consultation is required if symptoms appear. Long-term use may increase the risk of osteoporosis-related fractures, and hypomagnesemia may occur rarely, so magnesium levels should be checked periodically. Furthermore, this drug can suppress gastric acid secretion, increasing the risk of bacterial overgrowth in the gastrointestinal tract. If symptoms such as persistent diarrhea, respiratory distress, or fever develop, immediate notification to healthcare professionals is essential. Caution is needed as drowsiness may occur during driving or operating machinery. Drug interactions can occur when used in combination with other medications, especially with warfarin, methotrexate, atazanavir, and antibiotics. Consultation with a healthcare professional is essential in those cases. This medication should be swallowed whole and not chewed or crushed, and kept out of reach of children. During the use of this drug, regular blood and liver function tests should be conducted, and any abnormal symptoms should be reported immediately to healthcare professionals.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, fulminant hepatitis, hepatic dysfunction, jaundice, angina, pulmonary embolism, ventricular tachycardia, toxic epidermal necrolysis (Lyell's syndrome), Stevens-Johnson syndrome, interstitial pneumonia, hepatic encephalopathy, sudden death, coma, hyperammonemia, rhabdomyolysis, sense of direction disturbances, delirium, anaphylaxis, angioedema, systemic allergic reactions (hypotension, respiratory distress, facial swelling)

Mild side effects

  • Rash
  • hives
  • itching
  • decreased red blood cells
  • decreased white blood cells
  • increased white blood cells
  • increased eosinophils
  • increased neutrophils
  • decreased lymphocytes
  • anemia
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  • petechial hemorrhage
  • lymphadenopathy
  • hypochromic anemia
  • pancytopenia
  • agranulocytosis
  • decreased platelets
  • hemolytic anemia
  • elevated ALT
  • elevated AST
  • elevated ALP
  • elevated γ-GTP
  • elevated LDH
  • hypertension
  • myocardial infarction
  • ECG abnormalities
  • migraine
  • syncope
  • angina
  • heart block
  • palpitations
  • bradycardia

Not everyone experiences these, and they can vary from person to person.

Storage

This drug should be stored in a tightly sealed container to prevent air and moisture from entering. The storage temperature should be maintained between 1 and 30 degrees Celsius at room temperature. This will ensure the safety of the medication's effectiveness.

Appearance and packaging

Appearance

Pale yellow round enteric-coated tablet

Package unit

28 tablets/Alu-Alu (14 tablets/Alu-Alu*2)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.