Isocid Tablet (Esomeprazole Magnesium Trihydrate)

Adult dosage

This medicine should be swallowed with a liquid such as water and must not be chewed or crushed. Administer 40 mg once daily for 4 weeks. Patients whose esophagitis has not healed or whose symptoms persist should take it for an additional 4 weeks. 20 mg once daily. 20 mg once daily. If symptoms are not controlled after 4 weeks, further evaluation is needed. Once symptoms have improved, control subsequent symptoms by administering 20 mg once daily. In adults, 20 mg may be administered once daily as needed. For patients at high risk of developing gastric or duodenal ulcers due to nonsteroidal anti-inflammatory drug treatment, as-needed administration is not recommended for controlling recurring symptoms. Administer this medicine 20 mg in combination with amoxicillin 1 g and clarithromycin 500 mg twice daily for 7 days. 20 mg once daily. If symptoms are not controlled after 4 weeks, further evaluation is needed. Clinical studies exceeding 4 weeks have not been conducted. 20 mg once daily. The treatment period is 4∼8 weeks. 20 mg once daily. The recommended initial dose is 40 mg twice daily. Thereafter, the dose should be adjusted for each patient, and treatment should continue while clinical symptoms are present. Clinical data indicate that most patients can be controlled with doses of 80 ∼ 160 mg daily. Doses above 80 mg daily should be taken in 2 divided doses. Administer 40 mg once daily for 4 weeks after induction of prevention of rebleeding from gastric or duodenal ulcers with intravenous injection. No dose adjustment is necessary. Since there is limited experience in administering this medicine to patients with severe renal impairment, administer with caution. No dose adjustment is necessary in patients with mild to moderate hepatic impairment. In patients with severe hepatic impairment, the dose of this medicine should not exceed 20 mg. No dose adjustment is necessary.

Children's dosage

Adolescents aged 12 years or older: Treatment of erosive reflux esophagitis: Administer 40 mg once daily for 4 weeks. Patients whose esophagitis has not healed or whose symptoms persist should take it for an additional 4 weeks. Adolescents aged 12 years or older: Symptomatic treatment of gastroesophageal reflux disease without esophagitis: 20 mg once daily. If symptoms are not controlled after 4 weeks, further evaluation is needed. Adolescents aged 12 years or older: Once symptoms have improved, control subsequent symptoms by administering 20 mg once daily. Pediatric patients younger than 12 years: There is no experience with administering this medicine to pediatric patients younger than 12 years.

This medication should not be used in certain patients. For example, patients allergic or hypersensitive to this medication or its components should not receive it. Patients with hypersensitivity to penicillin or macrolide antibiotics also need to exercise caution when using this medication in combination. Specifically, patients currently on certain cardiovascular medications, those with a history of myocardial infarction, and breastfeeding women should not use this medication. This medication can cause various adverse reactions, with common ones including headache, abdominal pain, and diarrhea. Rarely, abnormalities in blood, nervous system issues, skin rash, or serious allergic reactions can occur, so if symptoms arise, immediate consultation with a physician is necessary. Long-term use may lead to electrolyte imbalance such as hypomagnesemia, so regular monitoring is needed. This medication reduces gastric acidity, which may affect the absorption of other medications; therefore, caution is required regarding interactions with co-administered drugs. Especially when used in conjunction with antiviral drugs or anticoagulants, dosage adjustments and monitoring per the doctor's instructions are necessary. The safety of this medication during pregnancy or breastfeeding has not been established, so caution is advised. In case of overdose, there is no specific antidote, and symptomatic treatment based on the symptoms will be required, and it should be stored out of reach of children. Long-term or high-dose use of this medication should be managed appropriately considering the increased risk of fractures and the possibility of gastric polyps.

Leukopenia, thrombocytopenia, agranulocytosis, pancytopenia, fever, angioedema, anaphylactic reaction, shock, peripheral edema, hyponatremia, hypomagnesemia, insomnia, anxiety, mental confusion, depression, aggression, hallucinations, headache, dizziness, paresthesia, drowsiness, taste disorder, blurred vision, bronchospasm, pancreatitis, abdominal pain, constipation, diarrhea, abdominal distension, nausea, vomiting, xerostomia, stomatitis, gastrointestinal candidiasis, microscopic colitis, elevated liver enzymes, hepatitis, liver failure, encephalopathy, dermatitis, itching, rash, urticaria, hair loss, photosensitivity, erythema multiforme, mucocutaneous syndrome, Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, eosinophilia and systemic symptoms associated drug reactions, fractures, arthralgia, myalgia, muscle weakness, focal segmental glomerulosclerosis, gynecomastia, asthenia, increased sweating, Clostridium difficile-associated diarrhea, abdominal bloating, allergic reactions, back pain, chest pain, retrosternal pain, facial edema, facial flushing, fatigue, fever, influenza-like illness, general edema, leg edema, lethargy, pain, rigidity, peripheral edema, flushing, hypertension, tachycardia, goiter, irritable bowel syndrome, exacerbation of constipation, dyspepsia, dysphagia, gastrointestinal developmental disorders, epigastric pain, belching, esophageal disorders, frequent bowel movements, gastroenteritis, gastrointestinal bleeding, hiccups, melena, oral disorders, pharyngeal disorders, rectal disorders, gastrointestinal symptoms, serologic gastrin elevation, tongue disorders, tongue edema, ulcerative stomatitis, vomiting, otalgia, tinnitus, anemia, hypochromic anemia, cervical lymphadenopathy, epistaxis, leukocytosis, leukopenia, thrombocytopenia, hyperbilirubinemia, liver function abnormalities, elevated ALT, elevated AST, diabetes, hyperuricemia, elevated ALP, thirst, vitamin B12 deficiency, weight gain, weight loss, exacerbation of arthritis, arthropathy, convulsions, fibromyalgia syndrome, hernia, rheumatic polymyalgia, arthralgia, anorexia, apathy, increased appetite, confusion, exacerbation of depression, hypertonicity, anxiety, sensory impairment, erectile dysfunction, insomnia, migraine, exacerbation of migraine, sleep disorders, tremor, dizziness, visual field defects, paresthesia, drowsiness, dysmenorrhea, menstrual disorders, vaginitis, exacerbation of asthma, cough, dyspnea, laryngeal edema, pharyngitis, rhinitis, sinusitis, acne, anal itching, rash, erythematous rash, papular rash, angioedema, dermatitis, itching, urticaria, increased sweating, otitis media, dysosmia, ageusia, parageusia, abnormal urination, albuminuria, cystitis, dysuria, fungal infection, hematuria, frequency of urination, candidiasis, genital candidiasis, polyuria, conjunctivitis, visual disturbances, duodenitis, esophagitis, esophageal stricture, esophageal ulcer, esophageal varices, gastric ulcer, gastritis, benign polyps or nodules, Barrett's esophagus, mucosal discoloration, hernia, systemic lupus erythematosus, cutaneous lupus erythematosus, hypocalcemia, hypokalemia, rhabdomyolysis

This medication should be stored in a tightly closed container to avoid exposure to air or moisture, at room temperature between 1 to 30 degrees Celsius. By doing so, the efficacy and safety of the medication can be maintained over time.

Appearance

Pale pink round film-coated tablet

Package unit

28 tablets/box [14 tablets/Alu-Alu × 2]