Tutopozin 5/160 mg

Adult dose

The recommended dosage of this medication is one tablet once daily, taken with water regardless of meals. It is advisable to take it at the same time every day (e.g., in the morning). Dose adjustments are recommended if blood pressure is not controlled with monotherapy of individual components (amlodipine or valsartan), as follows: - 5/80 mg: Administer to patients whose blood pressure is not adequately controlled with monotherapy of 5 mg amlodipine or 80 mg valsartan. - 5/160 mg: Administer to patients whose blood pressure is not adequately controlled with monotherapy of 5 mg amlodipine or 160 mg valsartan. - 10/160 mg: Administer to patients whose blood pressure is not adequately controlled with monotherapy of 10 mg amlodipine or 160 mg valsartan, or 5/160 mg. For patients taking valsartan and amlodipine concurrently, switching to this medication (which has the same constituent component dosages) may be considered for convenience. Patients with renal impairment: No dose adjustments are needed for patients with mild to moderate renal impairment (creatinine clearance ≥ 10 mL/min), but this medication should not be administered to patients with severe renal impairment (creatinine clearance < 10 mL/min) or dialysis patients. For moderate renal impairment patients, monitoring of potassium levels and creatinine is recommended. Patients with liver impairment: For patients with mild to moderate liver impairment, the daily maximum dose of valsartan should not exceed 80 mg. This medication should not be administered to patients with severe liver impairment, cholestatic liver cirrhosis, biliary obstruction, or cholestasis. Elderly patients aged 65 and over: Caution should be exercised when increasing the dosage. Pediatrics: Safety and efficacy for pediatric patients under 18 years of age have not been established, so administration of this medication is not recommended.

Child dose

Safety and efficacy for pediatric patients under 18 years of age have not been established, so administration of this medication is not recommended.

This medication can cause serious harm to the fetus if taken during the second and third trimesters of pregnancy, so it should be discontinued immediately if pregnancy is confirmed. Patients with allergies to this medication's active ingredients or similar ingredients, pregnant or breastfeeding women, individuals with severe kidney or liver dysfunction, or those with specific heart diseases should not take it. Individuals with a deficiency of sodium or body fluids should manage their condition prior to taking this medication, and if symptoms of hypotension occur during use, they should lie down and rest immediately and seek medical treatment if necessary. Those with high potassium levels should exercise caution when taking this medication along with potassium-raising drugs, and regular monitoring of serum potassium levels is advised. Particular caution is required for patients with kidney problems, those who have had a kidney transplant, those exhibiting symptoms of angioedema, as well as those with heart failure or post-myocardial infarction. This medication may cause side effects such as headache, dizziness, edema, hypotension, cough, and skin rash in some patients, so any unusual symptoms should be discussed with a healthcare professional. Dizziness or fatigue may occur when driving or operating machinery, so caution is necessary. This medication can interact with other antihypertensives, diuretics, potassium supplements, and certain anti-inflammatory medications, so any concurrent medications should be disclosed. Women who are pregnant or planning to become pregnant should not use this medication, and breastfeeding women should also avoid taking this drug. Safety and efficacy have not been established for children under 18 years of age, hence its use is not recommended. In cases of overdose, severe hypotension or cardiac abnormalities may occur, so care should be taken not to exceed the prescribed dosage. Regular monitoring of blood pressure, kidney function, and electrolytes is important during the use of this medication.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, mucosal pain in mouth/eyes, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities with cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urinary complications.

Mild side effects

• Nasopharyngitis
• influenza
• hypersensitivity
• visual impairment
• anxiety
• headache
• dizziness
• drowsiness
• orthostatic dizziness
• paraesthesia

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is important to maintain storage temperatures between 1 and 30 degrees Celsius.

Appearance

Dark yellow rectangular film-coated tablet

Package unit

30 tablets/box [(10 tablets/Alu-Alu x 3)]