Zaniem Tablets (Lercanidipine Hydrochloride)

Adult dose

As Lercanidipine Hydrochloride, administer orally at a dose of 5 to 10 mg once daily at least 15 minutes before meals. The dosage may be increased up to 20 mg depending on the patient's symptoms. Dosage adjustments should be made gradually, as it takes about two weeks for the maximum antihypertensive effect to be clearly observed.

This medication should not be administered to certain patients. For example, it should not be used in individuals allergic to this drug or similar medications, pregnant or breastfeeding women, patients with heart problems, patients with severe liver or kidney impairment, and children or adolescents under 18 years of age. Additionally, patients with cardiac function problems or mild hepatic or renal impairment, those who frequently consume alcohol, and the elderly should use this medication with caution. While taking this medication, symptoms such as facial flushing or swelling of the hands and feet, a sensation of rapid heartbeat, headaches, dizziness, indigestion, nausea, and abdominal pain may occur. Liver function abnormalities or gingival hyperplasia may occur rarely, so caution is necessary. Abruptly stopping this medication can worsen symptoms, so it should be gradually reduced when discontinuing. Care should be taken when driving or operating machinery due to dizziness or drowsiness. The drug is metabolized in the liver, so caution is necessary when taking it with other medications that affect liver function, and grapefruit juice or alcohol should be avoided as they can enhance the drug's effects. Women who are pregnant or breastfeeding should not take this medication as it may affect the fetus or newborn. Safety in children or adolescents under 18 years has not been established, hence it is not used in this population. The elderly require special attention, but dosage adjustment is not always necessary. In case of overdose, severe hypotension or heart problems may arise, requiring immediate visit to a medical facility for precise monitoring and appropriate treatment. Lastly, this medication should be kept out of the reach of children, and transferring it to another container may compromise its quality.

Serious side effects

• Severe allergic reactions
• respiratory problems
• liver abnormalities (jaundice)

Mild side effects

Flushing (including facial flushing), peripheral edema, palpitations, tachycardia, hypotension, chest pain, angina, headache, dizziness, weakness, fatigue, drowsiness, neurosis, indigestion, nausea, vomiting, abdominal pain, diarrhea, polyuria, frequent urination, gingival hyperplasia, rash, myalgia, body tremors, insomnia, dry mouth, hand numbness, cough, abdominal bloating, erectile dysfunction, arrhythmia, cold sweat, skin tingling, premature contractions, tongue stiffness, increased ventricular premature contractions.

This medication should be stored in a tightly closed container to protect it from air and moisture, and ideally kept at a temperature between 1 and 30 degrees Celsius at room temperature. Such storage will help maintain the effectiveness of the medication and allow for safe use.

Appearance

Yellow round film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle