Medication info
Duo Medi Tablet (Polycarbophil Calcium)

Duo Medi Tablet (Polycarbophil Calcium)

Prescription medicationTablet경구
Ingredient · strength
Calcium Polycarbophil›625mg / 1 tablet
Manufacturer / importer
구주제약(주)
Appearance
White oval film-coated tablets
Packaging
30 tablets/bottle, 500 tablets/bottle
Approval status
Active

MFDS item code 201603692 · Approved 2016.06.21 · Insurance code 669804800

Summary

Main use
Relief of symptoms of chronic constipation and diarrhea (such as irritable bowel syndrome)
Who takes it
Adults · Children
Adult dose
This medication should be administered orally with at least 250 mL of water or liquid. The dosage of Polycarbophil Calcium is 1,250 mg administered orally once daily for 1 to 4 times. The recommended initial adult dose is 1,250 to 2,500 mg per day, with a potential increase up to 5,000 mg per day. Results typically appear within 12 to 72 hours. It should not be taken right before bedtime, and at least 1 hour should be allowed for digestion before going to sleep.
Child dose
This medication should be administered orally with at least 250 mL of water or liquid. For children aged 6 to 12 years, the dosage of Polycarbophil Calcium is 625 mg administered orally once daily for 1 to 3 times. For children under 6 years old,

Ingredients

Manufacturer
구주제약(주)

Efficacy & effects

Relief of symptoms of chronic constipation and diarrhea (such as irritable bowel syndrome)

  • Chronic constipation
  • nonspecific diarrhea
  • constipation
  • diarrhea in irritable bowel syndrome
View approved original text

This medication is used to manage symptoms of chronic constipation, nonspecific diarrhea, and constipation and diarrhea in irritable bowel syndrome.

How to take

Adult dose

This medication should be administered orally with at least 250 mL of water or liquid. The dosage of Polycarbophil Calcium is 1,250 mg administered orally once daily for 1 to 4 times. The recommended initial adult dose is 1,250 to 2,500 mg per day, with a potential increase up to 5,000 mg per day. Results typically appear within 12 to 72 hours. It should not be taken right before bedtime, and at least 1 hour should be allowed for digestion before going to sleep.

Child dose

This medication should be administered orally with at least 250 mL of water or liquid. For children aged 6 to 12 years, the dosage of Polycarbophil Calcium is 625 mg administered orally once daily for 1 to 3 times. For children under 6 years old,

Precautions

This medication should not be used in certain patients. For example, it may be dangerous to administer to individuals with allergies to this medication or its ingredients, those with unexplained rectal bleeding, and those in severe dehydration. Additionally, it is advisable not to use this medication for patients who have swallowing difficulties or those in a position that may cause the medication to reflux. Patients with issues involving the colon or bowel function or acute abdominal conditions, bowel obstruction, or bowel strictures may experience an exacerbation of symptoms from using this medication. Patients with hypercalcemia, kidney stones, or severe renal failure should not take this medication. It should also not be given to patients with severe abdominal pain, nausea, or vomiting symptoms. Patients who need to limit calcium intake or those taking active vitamin D preparations should use this medication cautiously, and patients on cardiac glycosides should also exercise caution. Patients with low gastric acid secretion or those who have undergone gastric resection, those undergoing dialysis or with mild renal failure should also be cautious when taking this medication. This medication may cause allergic reactions such as rashes or itching; if such symptoms occur, use should be discontinued, and the patient should consult a physician. Adverse reactions may include nausea, vomiting, abdominal pain, diarrhea, constipation, and symptoms related to digestive issues, liver function abnormalities, hypercalcemia, swelling, headache, etc. Taking this medication without sufficient water can cause it to become lodged in the throat or esophagus, resulting in blockage or choking risks. Therefore, it must be taken with water. If chest pain, difficulty breathing, or swallowing difficulties occur after taking, immediate cessation of use and consultation with a healthcare professional is necessary. This medication is for symptom relief; if symptoms do not improve after more than 7 days of use, a physician should be consulted, and long-term use (more than 3 months) should be monitored closely for adverse reactions. When taken with other medications, it is advisable to maintain at least a 2-hour interval as it may affect absorption. Special caution should be exercised when taken with tetracycline antibiotics or fluoroquinolone antimicrobial agents, and the risk of hypercalcemia increases when combined with active vitamin D preparations. Taking this medication with calcium supplements may lead to hypercalcemia, and side effects such as arrhythmia may occur with the use of cardiac glycosides, thus caution is needed. Moreover, taking this medication with acid secretion suppressants may reduce its efficacy. Women who are pregnant or may become pregnant should only take this medication if the therapeutic benefits outweigh the risks, and safety for children has not been established. Elderly patients may have reduced kidney function, making them susceptible to hypercalcemia, so dose adjustments and careful monitoring are advised. This medication should be kept out of reach of children and stored in a cool, dry place at room temperature. It is best to store it in the original container and avoid transferring it to another container.

Side effects and when to seek care immediately

Serious side effects

  • Headache
  • swelling
  • chest pain
  • vomiting
  • difficulty breathing

Mild side effects

  • Rash
  • itching
  • leukopenia
  • nausea
  • vomiting
  • dry mouth
  • abdominal bloating
  • diarrhea
  • constipation
  • abdominal pain
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  • flatulence
  • elevated AST
  • elevated ALT
  • bowel obstruction
  • fecal impaction
  • hypercalcemia
  • swelling
  • headache
  • hematuria
  • proteinuria
  • elevated LDH
  • elevated γ-GTP
  • elevated ALP
  • elevated total bilirubin

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container that allows for air circulation, at a temperature between 1 degree and 30 degrees Celsius. Proper storage can maintain the drug's efficacy and prevent deterioration.

Appearance and packaging

Appearance

White oval film-coated tablets

Package unit

30 tablets/bottle, 500 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.