Esome Tablet 20 mg (Esomeprazole Magnesium Trihydrate)

Adult dosage

This medication should be swallowed with liquid such as water and should not be chewed or crushed. 1. Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks. - If esophagitis does not resolve or symptoms continue, an additional 4 weeks of treatment is necessary. - Maintenance therapy for prevention of recurrence in patients with esophagitis: 20 mg once daily. - Symptom treatment for gastroesophageal reflux disease without esophagitis.

Children's dosage

Adolescents aged 12 years and older - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks. - If esophagitis persists or symptoms continue, additional treatment for 4 weeks. - Treatment of gastroesophageal reflux disease without esophagitis.

This medication should not be administered to certain patients. For example, patients with an allergy to this medication or its components, or those who have previously experienced hypersensitivity reactions to benzimidazole derivatives should not use it. Additionally, when used in combination with penicillin antibiotics or macrolide antibiotics for the treatment of Helicobacter pylori infection, patients allergic to those antibiotics should also avoid taking this medication. This medication may cause serious side effects when used in combination with certain heart-related medications, so it should not be administered to patients taking terfenadine, cisapride, pizotifen, or astemizole. Moreover, it is also advisable for patients taking certain antiviral drugs like atazanavir and nelfinavir, as well as nursing mothers, to avoid using this medication. Patients with a history of myocardial infarction or those taking rilpivirine containing products should also not be administered this medication. This medication may cause various adverse reactions, with the most common symptoms being headache, abdominal pain, diarrhea, constipation, nausea, and vomiting. Rarely, serious side effects may occur, including blood-related problems, allergic reactions, hypomagnesemia, psychiatric symptoms, liver function abnormalities, skin rashes, myalgia, and nephritis, so if symptoms appear, you should consult a doctor immediately. Regular check-ups are necessary during long-term use, and care should be taken especially if used for more than one year as the risk of hypomagnesemia and fractures may increase. This medication suppresses gastric acid secretion which may promote bacterial growth in the stomach, slightly increasing the risk of infection. Additionally, interactions with other medications may occur during use, so if taken with warfarin, digoxin, methotrexate, clopidogrel, etc., monitoring serum concentration changes is essential. The safety of this medication during pregnancy has not been adequately established, so it should be used cautiously based on the doctor's judgment, and it is preferable to avoid use while breastfeeding. In case of overdose, since there are no specific antidotes, you should visit a hospital immediately for symptomatic treatment, and keep it out of reach of children.

Serious side effects

Hives, angioedema, anaphylactic reactions, shock, hypomagnesemia, hypocalcemia, hypokalemia, confusion, hepatitis, jaundice, liver failure, encephalopathy, skin mucous membrane syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell's syndrome), acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), renal interstitial nephritis, Clostridium difficile-associated diarrhea, sudden and severe.

Mild side effects

Headache, dizziness, sensory disturbances, drowsiness, taste disorders, blurred vision, bronchospasm, abdominal pain, constipation, diarrhea, abdominal distension, nausea, vomiting, dry mouth, stomatitis, gastrointestinal candidiasis, dermatitis, itching, rash, hair loss, photosensitivity, fractures, arthralgia, myalgia, gynecomastia, weakness, increased sweating, Clostridium difficile-associated diarrhea, allergic reactions, back pain, chest pain, sternum pain, facial swelling, facial flushing.

This medication should be stored in a tightly sealed container to protect it from air and moisture. The recommended storage temperature is between 1 and 30 degrees Celsius at room temperature. This will help maintain the medication's effectiveness longer.

Appearance

Pink round film-coated tablet

Package unit

14 tablets/blister × 2